Uniprot ID	A0R5D9
Uniprot Name	TOP1_MYCS2
Taxonomy ID	246196
Sequence	M A G G D R G S G G T G N V R R L V I V E S P T K A R K I A G Y L G S N Y V V E S S R G H I R D L P R N A A D V P A K F K S E P W A R L G V N V D Q N F E P L Y I V S P E K K S T V T E L K G L L K D V D E L Y L A T D G D R E G E A I A W H L L E T L K P R V P V K R M V F H E I T E P A I R N A A E N P R D L D I A L V D A Q E T R R I L D R L Y G Y E V S P V L W K K V A P K L S A G R V Q S V A T R I I V Q R E R E R M A F H S A S Y W D V T A E L D A S V S D P S A S P P K F T A K L N T V D G R R V A T G R D F D S L G Q L K R P D E V L V L D E A S A G A L A S G L R G A Q L A V T S V E Q K P Y T R R P Y A P F M T S T L Q Q E A A R K L R F S S E R T M S I A Q R L Y E N G Y I T Y M R T D S T T L S E S A I N A A R T Q A R Q L Y G E E Y V H P S P R Q Y T R K V K N A Q E A H E A I R P A G D V F Q T P G Q L H S A L D T D E F R L Y E L I W Q R T V A S Q M A D A R G T T L S L R I G G S A S S G E Q V V F N A S G R T I T F P G F L K A Y V E S I D E L A G G E S D D A E S R L P N L T Q G Q R V D A A D L S A D G H Q T S P P A R Y T E A S L I K A L E E L G I G R P S T Y S S I I K T I Q D R G Y V Q K K G S A L V P S W V A F A V V G L L E Q H F G R L V D Y D F T A A M E D E L D E I A N G Q E Q R T N W L N N F Y F G G E H G V E G S I A R A G G L K Q L V G G N L E G I D A R E V N S I K V F D D S E G R P V Y V R V G R N G P Y L E R M V D D P D N P G E Q K P Q R A N L K E D L T P D E L T P E L A E K L F A T P Q E G R S L G I D P E T G H E I V A K D G R F G P Y V T E V L P E P E D G G D D G T A G T P A K K G K K P T G P K P R T G S L F R S M D L E T V T L E D A L K L L S L P R V V G V D P T T N E E I T A Q N G R Y G P Y L K R G T D S R S L A T E D Q I F T I T L D E A L K I Y A E P K R R G R Q A A S A P P L R E L G N D P V S G K P M V I K D G R F G P Y V T D G E T N A S L R K G D D V L T I T D E R A S E L L A D R R A R G P V K K K A P A K K A A K K A P A K K A A A K K A
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000255|HAMAP-Rule:MF_00952, ECO:0000269|PubMed:9593741}; Note=Binds two Mg(2+) per subunit. {ECO:0000255|HAMAP-Rule:MF_00952};
Active site	ACT_SITE 339 339 O-(5'-phospho-DNA)-tyrosine intermediate. {ECO:0000255|HAMAP-Rule:MF_00952, ECO:0000305|PubMed:9593741}.
Pfam	PF01131 PF01751 PF13368
InterPro	IPR000380 IPR003601 IPR023406 IPR013497 IPR013824 IPR013825 IPR013826 IPR023405 IPR003602 IPR005733 IPR028612 IPR025589 IPR006171 IPR034149