Uniprot ID	A1KZ92
Uniprot Name	PXDNL_HUMAN
Taxonomy ID	9606
Sequence	M E P R L F C W T T L F L L A G W C L P G L P C P S R C L C F K S T V R C M H L M L D H I P Q V P Q Q T T V L D L R F N R I R E I P G S A F K K L K N L N T L L L N N N H I R K I S R N A F E G L E N L L Y L Y L Y K N E I H A L D K Q T F K G L I S L E H L Y I H F N Q L E M L Q P E T F G D L L R L E R L F L H N N K L S K I P A G S F S N L D S L K R L R L D S N A L V C D C D L M W L G E L L Q G F A Q H G H T Q A A A T C E Y P R R L H G R A V A S V T V E E F N C Q S P R I T F E P Q D V E V P S G N T V Y F T C R A E G N P K P E I I W I H N N H S L D L E D D T R L N V F D D G T L M I R N T R E S D Q G V Y Q C M A R N S A G E A K T Q S A M L R Y S S L P A K P S F V I Q P Q D T E V L I G T S T T L E C M A T G H P H P L I T W T R D N G L E L D G S R H V A T S S G L Y L Q N I T Q R D H G R F T C H A N N S H G T V Q A A A N I I V Q A P P Q F T V T P K D Q V V L E E H A V E W L C E A D G N P P P V I V W T K T G G Q L P V E G Q H T V L S S G T L R I D R A A Q H D Q G Q Y E C Q A V S S L G V K K V S V Q L T V K P K A L A V F T Q L P Q D T S V E V G K N I N I S C H A Q G E P Q P I I T W N K E G V Q I T E S G K F H V D D E G T L T I Y D A G F P D Q G R Y E C V A R N S F G L A V T N M F L T V T A I Q G R Q A G D D F V E S S I L D A V Q R V D S A I N S T R R H L F S Q K P H T S S D L L A Q F H Y P R D P L I V E M A R A G E I F E H T L Q L I R E R V K Q G L T V D L E G K E F R Y N D L V S P R S L S L I A N L S G C T A R R P L P N C S N R C F H A K Y R A H D G T C N N L Q Q P T W G A A L T A F A R L L Q P A Y R D G I R A P R G L G L P V G S R Q P L P P P R L V A T V W A R A A A V T P D H S Y T R M L M H W G W F L E H D L D H T V P A L S T A R F S D G R P C S S V C T N D P P C F P M N T R H A D P R G T H A P C M L F A R S S P A C A S G R P S A T V D S V Y A R E Q I N Q Q T A Y I D G S N V Y G S S E R E S Q A L R D P S V P R G L L K T G F P W P P S G K P L L P F S T G P P T E C A R Q E Q E S P C F L A G D H R A N E H L A L A A M H T L W F R E H N R M A T E L S A L N P H W E G N T V Y Q E A R K I V G A E L Q H I T Y S H W L P K V L G D P G T R M L R G Y R G Y N P N V N A G I I N S F A T A A F R F G H T L I N P I L Y R L N A T L G E I S E G H L P F H K A L F S P S R I I K E G G I D P V L R G L F G V A A K W R A P S Y L L S P E L T Q R L F S A A Y S A A V D S A A T I I Q R G R D H G I P P Y V D F R V F C N L T S V K N F E D L Q N E I K D S E I R Q K L R K L Y G S P G D I D L W P A L M V E D L I P G T R V G P T L M C L F V T Q F Q R L R D G D R F W Y E N P G V F T P A Q L T Q L K Q A S L S R V L C D N G D S I Q Q V Q A D V F V K A E Y P Q D Y L N C S E I P K V D L R V W Q D C C A D C R S R G Q F R A V T Q E S Q K K R S A Q Y S Y P V D K D M E L S H L R S R Q Q D K I Y V G E D A R N V T V L A K T K F S Q D F S T F A A E I Q E T I T A L R E Q I N K L E A R L R Q A G C T D V R G V P R K A E E R W M K E D C T H C I C E S G Q V T C V V E I C P P A P C P S P E L V K G T C C P V C R D R G M P S D S P E K R
Cofactor	COFACTOR: Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Note=Binds 1 Ca(2+) ion per subunit. {ECO:0000250}; COFACTOR: Name=heme b; Xref=ChEBI:CHEBI:60344; Evidence={ECO:0000250}; Note=Binds 1 heme b (iron(II)-protoporphyrin IX) group covalently per subunit. {ECO:0000250};
Active site	ACT_SITE 812 812 Proton acceptor. {ECO:0000255|PROSITE-ProRule:PRU00298}.
Pfam	PF03098 PF07679 PF13855 PF00093
InterPro	IPR000483 IPR019791 IPR010255 IPR037120 IPR007110 IPR036179 IPR013783 IPR013098 IPR003599 IPR003598 IPR001611 IPR003591 IPR032675 IPR034824 IPR029610 IPR001007