Uniprot ID	C5DN02
Uniprot Name	ARO1_LACTC
Taxonomy ID	559295
Sequence	M K V E L S K V P I L G K D V V H V G F D I A D H I V D T I F Q S C P S S T Y V V I N D T N V E K I P H Y V D L C G E L Q A K L K S G S R I L Q Y S V K P G E A H K T R E Q K A A I E D Y L L S E G C T R D T V I I A V G G G V I G D M I G Y V A S T F M R G V R V V Q V P T S L L A M V D S S I G G K T A V D T P L G K N F I G A F W Q P Q F V F V D I K W L E T L P K R E F I N G I A E V I K T A C I W N A E E F A R L E E N A D L F L Q V V N G S K T T Q V S V Q G Q V H E L S L T N I D A M L E H V Y R L V L E S I K V K T H V V S S D E R E A G L R N L L N F G H T I G H A Y E A I L T P Q A L H G E C V S I G M I K E A E L S R Y L N I L S P T Q V A R L T K I L A A Y G L P I S P D Q K W F K D L T L N K K T P L D V L L K K M S I D K K N D G S K K K A V L L E T I G K C Y G T S A H V V S D E D I R F V L T D E T L V Y P F K T L E N G Q E K T I V P P G S K S I S N R A L I L A A L G E G T C K I K N L L H S D D T K H M L H A V Q Q L K G A T I T W E D N G E T V V L K G H G G S T L Q A T A E P L Y L G N A G T A S R F L T S V A A L V N S T S S Q K S V V L T G N A R M Q E R P I G P L V D S L R E N G I S I D Y L N K E K S L P L K I N T D S N F K G G R I E L A A T V S S Q Y V S S I L M C A P Y A E E P V T L A L V G G K P I S K L Y I D M T I K M M E K F G I Y V K A S T E E P N T Y H I P K G H Y V N P P E Y V I E S D A S S A T Y P L A Y A A M T G T T V T V P N I G F E S L Q G D A R F A R D V L K P M G C S V T Q T E T S T T V T G P P V G G L K P L K H V D M E P M T D A F L T A C V V A A V A H D G K E G S R N T T T I E G I A N Q R V K E C N R I L A M V D E L A K F G V E A N E L P D G I Q V H G L S S I D K L K V P E A I H S Y D D H R V A M S F S L L A G M V G A T K D A L S E P V R I L E R S C T G K T W P G W W D V L H T Q L G A K L D G S E P L Q S A V K K N S N S S I V I I G M R A A G K T T V S S W C A N A L G F K F L D L D T V F E E Q Y K K G S V K E F V A E H G W D A F R A T E T K I F E E S V K K Y G E G Y V L S T G G G I V E G A A S R K S L K Q F A S Q G G I V L H L H R D I D E T I K F L N S D P T R P A Y N E D I R N V W E R R E E W Y K E C A N F T F Y A P H C T S S T Q F N Q L R K T F E T F I R T I S G K R E V K I P T N R S S F V C L T F D D L A A H K E K I P D I T A G C S A V E L R V D Q L K S Y D L D F V A K Q L S I L R L A S S S L P I I F T I R T K S Q G G Q F P D D D K S T L G S L L S L A L E V G V E F V D M E L T L S S E L Q Y S L V N N K R N T K I I G S H H D F D A K F D W N D S E W E N R Y N Q A L S L D V D V V K F V G T A K D F E D N L K L E Q F R L Q H T A K P L I A I N M T D V G K M S R V L N T V L T P V T S S L L P S A S A P G Q L T L S Q I N E I Y T L L G G F S A K N F Y V V G S P I S H S R S P V L H N T G Y K I L G L P H K F E K F E T S S A S E V K D K L L S K C K L G G L A V T I P L K L D I M E F M D E L S E S A K L I G A V N T V I P L G D G K F K G D N T D W L G I Y N S F L A N G V P E N V R G N S G F V I G A G G T S R A A V Y A L H Q L G C S D I H L V N R T V E K P H D L K K S F P S E Y N L H V L E D S Q Q A E G I S G S V A L A V S C V P A D K P L D D N L L A R V R A V L A K A Q G T S F K P T L L E A A Y K P A V T P M M K T A S D E F S W H I I P G S Q M L V H Q G V A Q F Q L W T G F R A P F N A I Y S A V T E E Q A
Cofactor	COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 2 Zn(2+) ions per subunit.;
Active site	ACT_SITE 267 267 Proton acceptor; for 3-dehydroquinate synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 282 282 Proton acceptor; for 3-dehydroquinate synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 844 844 For EPSP synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 1188 1188 Proton acceptor; for 3-dehydroquinate dehydratase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 1217 1217 Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.
Pfam	PF01761 PF01487 PF00275 PF18317 PF01488 PF08501 PF01202
InterPro	IPR018508 IPR013785 IPR016037 IPR030960 IPR001381 IPR001986 IPR036968 IPR006264 IPR023193 IPR036291 IPR027417 IPR008289 IPR013792 IPR041121 IPR031322 IPR013708 IPR010110 IPR000623 IPR023000 IPR006151