Uniprot ID	C7GIN5
Uniprot Name	ARO1_YEAS2
Taxonomy ID	574961
Sequence	M V Q L A K V P I L G N D I I H V G Y N I H D H L V E T I I K H C P S S T Y V I C N D T N L S K V P Y Y Q Q L V L E F K A S L P E G S R L L T Y V V K P G E T S K S R E T K A Q L E D Y L L V E G C T R D T V M I A I G G G V I G D M I G F V A S T F M R G V R V V Q V P T S L L A M V D S S I G G K T A I D T P L G K N F I G A F W Q P K F V L V D I K W L E T L A K R E F I N G M A E V I K T A C I W N A D E F T R L E S N A S L F L N V V N G A K N V K V T N Q L T N E I D E I S N T D I E A M L D H T Y K L V L E S I K V K A E V V S S D E R E S S L R N L L N F G H S I G H A Y E A I L T P Q A L H G E C V S I G M V K E A E L S R Y F G I L S P T Q V A R L S K I L V A Y G L P V S P D E K W F K E L T L H K K T P L D I L L K K M S I D K K N E G S K K K V V I L E S I G K C Y G D S A Q F V S D E D L R F I L T D E T L V Y P F K D I P A D Q Q K V V I P P G S K S I S N R A L I I A A L G E G Q C K I K N L L H S D D T K H M L T A V H E L K G A T I S W E D N G E T V V V E G H G G S T L S A C A D P L Y L G N A G T A S R F L T S L A A L V N S T P S Q K Y I V L T G N A R M Q Q R P I A P L V D S L R A N G T K I E Y L N N E G S L P I K V Y T D S V F K G G R I E L A A T V S S Q Y V S S I L M C A P Y A E E P V T L A L V G G K P I S K L Y V D M T I K M M E K F G I N V E T S T T E P Y T Y Y I P K G H Y I N P S E Y V I E S D A S S A T Y P L A F A A M T G T T V T V P N I G F E S L Q G D A R F A R D V L K P M G C K I T Q T A T S T T V S G P P V G T L K P L K H V D M E P M T D A F L T A C V V A A I S H D S D P N S A N T T T I E G I A N Q R V K E C N R I L A M A T E L A K F G V K T T E L P D G I Q V H G L N S I K D L K V P S D S S G P V G V C T Y D D H R V A M S F S L L A G M V N S Q N E R D E V A N P V R I L E R H C T G K T W P G W W D V L H S E L G A K L D G A E P L E C T S K K N S K K S V V I I G M R A A G K T T I S K W C A S A L G Y K L V D L D E L F E Q Q H N N Q S V K Q F V V E N G W E K F R E E E T R I F K E V I Q N Y G D D G Y V F S T G G G I V E S A E S R K A L K D F A S S G G Y V L H L H R D I E E T I V F L Q S D P S R P A Y V E E I R E V W N R R E E W Y K E C S N F S F F A P H C S A E A E F Q A L R R S F S K Y I A T I T G V R E I E I P S G R S A F V C L T F D D L T E Q T E N L T P I C Y G C E A V E V R V D H L A N Y S A D F V S K Q L S I L R K A T D S I P I I F T V R T K K Q G G N F P D E E F K T L R E L Y D I A L K N G V E F L D L E L T L P T D I Q Y E V I N K R G N T K I I G S H H D F Q G L Y S W D D A E W E N R F N Q A L T L D V D V V K F V G T A V N F E D N L R L E H F R D T H K N K P L I A V N M T S K G S I S R V L N N V L T P V T S D L L P N S A A P G Q L T V A Q I N K M Y T S M G G I E P K E L F V V G K P I G H S R S P I L H N T G Y E I L G L P H K F D K F E T E S A Q L V K E K L L D G N K N F G G A A V T I P L K L D I M Q Y M D E L T D A A K V I G A V N T V I P L G N K K F K G D N T D W L G I R N A L I N N G V P E Y V G H T A G L V I G A G G T S R A A L Y A L H S L G C K K I F I I N R T T S K L K P L I E S L P S E F N I I G I E S T K S I E E I K E H V G V A V S C V P A D K P L D D E L L S K L E R F L V K G A H A A F A P T L L E A A Y K P S V T P V M T I S Q D K Y Q W H V V P G S Q M L V H Q G V A Q F E K W T G F K A P F K A I F D A V T K E
Cofactor	COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Note=Binds 2 Zn(2+) ions per subunit.;
Active site	ACT_SITE 268 268 Proton acceptor; for 3-dehydroquinate synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 283 283 Proton acceptor; for 3-dehydroquinate synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 853 853 For EPSP synthase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 1198 1198 Proton acceptor; for 3-dehydroquinate dehydratase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.; ACT_SITE 1227 1227 Schiff-base intermediate with substrate; for 3-dehydroquinate dehydratase activity. {ECO:0000255|HAMAP-Rule:MF_03143}.
Pfam	PF01761 PF01487 PF00275 PF18317 PF01488 PF08501 PF01202
InterPro	IPR018508 IPR013785 IPR016037 IPR030960 IPR001381 IPR001986 IPR036968 IPR006264 IPR023193 IPR036291 IPR027417 IPR008289 IPR013792 IPR041121 IPR031322 IPR013708 IPR010110 IPR000623 IPR023000 IPR006151