Uniprot ID	D3ZAW2
Uniprot Name	PISD_RAT
Taxonomy ID	10116
Sequence	M A V A G G R G C V R S L R E G V L W R S S P C H C D Y T A T R H F L G A L Q K L P L Q A W V R K V H T A P L R T L F L L R P V P I L L A A G G G Y A G Y R Q Y E K Y R E R Q L E K L G L E I P P K L A S H W E V S L Y K S V P T R L L S R A C G R L N Q V E L P S W L R R P V Y S L Y I W T F G V N M T E A A V E D L Q H Y R N L S E F F R R K L K P Q A R P V C G L H S V I S P S D G K I L T F G Q V K N S E V E Q V K G V T Y S L E S F L G P R A C T E D L P F P P A S S C D S F R N Q L V T R E G N E L Y H C V I Y L A P G D Y H C F H S P T D W T V S H R R H F P G S L M S V N P G M A R W I K E L F C H N E R V V L T G D W K H G F F S L T A V G A T N V G S I R I H F D Q D L H T N S P S Y S K G S Y N D L S F V T H A N K E G I P M R K G E P L G E F N L G S T I V L I F E A P K D F N F R L K A G Q K I L F G E A L G S L
Cofactor	COFACTOR: Name=pyruvate; Xref=ChEBI:CHEBI:15361; Evidence={ECO:0000255|HAMAP-Rule:MF_03208}; Note=Binds 1 pyruvoyl group covalently per subunit. {ECO:0000255|HAMAP-Rule:MF_03208};
Active site	ACT_SITE 188 188 Charge relay system; for autoendoproteolytic cleavage activity. {ECO:0000255|HAMAP-Rule:MF_03208}.; ACT_SITE 264 264 Charge relay system; for autoendoproteolytic cleavage activity. {ECO:0000255|HAMAP-Rule:MF_03208}.; ACT_SITE 375 375 Charge relay system; for autoendoproteolytic cleavage activity. {ECO:0000255|HAMAP-Rule:MF_03208}.; ACT_SITE 375 375 Schiff-base intermediate with substrate; via pyruvic acid; for decarboxylase activity. {ECO:0000255|HAMAP-Rule:MF_03208}.
Pfam	PF02666
InterPro	IPR003817 IPR033177 IPR033661