Uniprot ID	E9Q4S1
Uniprot Name	PDE8B_MOUSE
Taxonomy ID	10090
Sequence	M G C A P S I H V S Q S G V I Y C R D S D E S N S P R Q T S S V S Q G P T A P L H G L F V Q T D A A D A M P P S R A A G P P G A V R V R R S R A E L G S G S S T G S S G P A T T T C R G R R R H C C S S A E A E T Q T S Y T S V K V L L I F A K E D S Q S D G F W W A C D R A G Y R C N I A R T P E S A L E C F L D K H H E I I V I D H R Q S R N F D A E A V C R S I R A T N P S E H T V I L A V V S Q A S D D H E E A S V L P L L H A G F N R R F M E N S S I I A C Y N E L I Q I E H G E V R S Q F K L R A C N S V F T A L D H C H E A I E I T S D D H V I Q Y V N P A F E R M M G Y H K G E L L G K E L A D L P K S D K N R A D L L D T I N T C I K K G K E W Q G V Y Y A R R K S G D S I Q Q H V K I T P V I G Q G G K I R H F V S L K K L C C T T D S N K Q I H R I H R D S G D N S Q T E P H S F R H K S R R K E S I D V K S I S S R G S D A P S L Q N R R Y P S M A R I H S M T I E A P I T K V I N I I N A A Q E N S P V T V A E A L D R V L E I L R T T E L Y S P Q L G T K D E D P H T S D L V G G L M T D G L R R L S G N E Y V F T K N V H H S H S H L S M P I T I N D V P P S I A Q L L D N E E S W D F N I F E L E A V T H K R P L V Y L G L K V F S R F G V C E F L N C T E T T L R A W L Q V I E A N Y H S S N A Y H N S T H A A D V L H A T A F F L G K E R V K G S L D Q L D E V A A L I A A T V H D V D H P G R T N S F L C N A G S E L A V L Y N D T A V L E S H H T A L A F Q L T V K D T K C N I F K N I D R N H Y R T L R Q A I I D M V L A T E M T K H F E H V N K F V N S I N K P L A A E S E G S D C E C N P T G K N F P E N Q I L I K R M M I K C A D V A N P C R P L D L C I E W A G R I S E E Y F A Q T D E E K R Q G L P V V M P V F D R N T C S I P K S Q I S F I D Y F I T D M F D A W D A F A H L P A L M Q H L A D N Y K H W K T L D D L K C K T L R L P S D S
Cofactor	COFACTOR: Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; Evidence={ECO:0000250}; Note=Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. {ECO:0000250};
Active site	ACT_SITE 595 595 Proton donor. {ECO:0000250|UniProtKB:O76083}.
Pfam	PF13426 PF08629 PF00233
InterPro	IPR003607 IPR000014 IPR035965 IPR023088 IPR002073 IPR036971 IPR023174 IPR013938