Uniprot ID	O19183
Uniprot Name	PGH2_HORSE
Taxonomy ID	9796
Sequence	M L A R A L L L C V A L A L G H A A N P C C S N P C Q N R G V C M S V G F D Q Y Q C D C T R T G F Y G E N C S T P E F L T R I K L F L K P T P N T V H Y I L T H F K G V W N I V N S F P F L R N A V M K Y V L V S R S H L I E S P P T Y N A Q Y G Y K S W E S F S N L S Y Y T R A L P P V A D G C P T P M G V K G K K E L P D S K E I V E K F L L R R K F I P D P Q G T N M M F A F F A Q H F T H Q F F K T D P K R G P A F T K G L G H G V D L S H I Y G E T L D R Q H K L R L F K D G K M K Y Q I I N G E V Y P P T V K D T Q V E M I Y P P H I P E H L R F A V G Q E V F G L V P G L M M Y A T I W L R E H N R V C D V L K Q E H P E W D D E R L F Q T S R L I L I G E T I K I V I E D Y V Q H L S G Y H F K L K F D P E L L F N Q Q F Q Y Q N R I A A E F N T L Y H W H P L L P D T F Q I D D Q E Y N F Q Q F L Y N N S I L L E H G L T Q F V E S F S R Q I A G R V A G G R N V P A A A Q K I A K A S I D Q S R E M K Y Q S L N E Y R K R F R L T P Y K S F E E L T G E K E M A A E L E A L Y G D I D A M E L Y P A L L V E K P R P D A I F G E T M V E L G A P F S L K G L L G N P I C S P D Y W K P S T F G G E V G F K I I N T A S I Q S L I C N N V K G C P F T A F S V Q D P Q L S K A V T I N A S A S H S G L D D V N P T V L L K E R S T E L
Cofactor	COFACTOR: Name=heme b; Xref=ChEBI:CHEBI:60344; Evidence={ECO:0000250|UniProtKB:Q05769}; Note=Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit. {ECO:0000250|UniProtKB:Q05769};
Active site	ACT_SITE 193 193 Proton acceptor. {ECO:0000255|PROSITE-ProRule:PRU00298}.; ACT_SITE 371 371 For cyclooxygenase activity. {ECO:0000250|UniProtKB:Q05769}.
Pfam	PF03098 PF00008
InterPro	IPR029576 IPR000742 IPR019791 IPR010255 IPR037120