Uniprot ID	O20250
Uniprot Name	TKTC_SPIOL
Taxonomy ID	3562
Sequence	M A A S S S L S T L S H H Q T L L S H P K T H L P T T P A S S L L V P T T S S K V N G V L L K S T S S S R R L R V G S A S A V V R A A A V E A L E S T D I D Q L V E K S V N T I R F L A I D A V E K A N S G H P G L P M G C A P M G H I L Y D E I M R Y N P K N P Y W F N R D R F V L S A G H G C M L Q Y A L L H L A G Y D S V L E E D L K T F R Q W G S R I P G H P E N F E T P G V E V T T G P L G Q G I A N A V G L A L A E K H L A A R F N K P D A E I V D H Y T Y V I L G D G C Q M E G I A Q E A C S L A G H W G L G K L I A F Y D D N H I S I D G D T A I A F T E S V D L R F E A L G W H V I W V K N G N T G Y D E I R A A I K E A K T V T D K P T L I K V T T T I G F G S P N K S N S Y S V H G S A L G S K E V E A T R Q N L G W P Y E P F H V P E E V K K H W S R H T P E G A S L E A E W N T K F A E Y E K K Y P E D A T E F K S I T T G E F P A G W E K A L P T Y T P E T P G D A T R N L S Q Q C L N A L A K V I P G L L G G S A D L A S S N M T L L K M F G D F R R T H R K K E T F R F G V R E H G M G A I C N G I C L H S P G F V P Y C A T F F V F T D Y M R G A M R I S A L S E A G V I Y V M T H D S I G L G E D G P T H Q P I E A L S K F P A M P N I L M L R P A D G N E T A G S Y K V A V E N R K T P S I L A L S R K K L P N L P G T S I E G V E K G G Y T I T D N S S G N K P D V I L I G T G S E L E I A A K A G D E L R K E G K A V R V V S F V S W E L F E K Q S D E Y K E S V L P S D V T A R V S I E A G S T F G W H K I V G S K G K A I G I D K F G A S A P A G K I Y Q E Y G I T V E A V V E A A K S V C
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000250}; Note=Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+). {ECO:0000250}; COFACTOR: Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937; Evidence={ECO:0000250}; Note=Binds 1 thiamine pyrophosphate per subunit. {ECO:0000250};
Active site	ACT_SITE 488 488 Proton donor. {ECO:0000250}.
Pfam	PF02779 PF02780 PF00456
InterPro	IPR029061 IPR009014 IPR005475 IPR005478 IPR033248 IPR033247 IPR005474