Uniprot ID	O62725
Uniprot Name	PGH2_NEOVI
Taxonomy ID	452646
Sequence	M L A R A G L L C A S L S P P H A A N P C C S N P C Q N Q G V C M S I G F D Q Y M C D C S R T G F Y G E N C S T P E F L T R V K L L L K P T P N T V H Y I L T H F K G V W N I V N K I P F L A D V I M K Y V R T S R S H C I E P P P T Y N V H Y A Y K S W E A F S N L S Y Y T R A L P P V A D D C P T P M G V K G K K E L P D S K E I V E K F L L R R K F I P D P Q G T N M M F A F F A Q H F T H Q F F K T D H K R G P G F T K G L G H G V D L S H V Y G E T L D R Q H K L R L F K D G K M K Y Q V I D G E V Y P P T V K D T Q V E M I Y P P H V P E H L R F A V G Q E V F G L V P G L M M Y A T I W L R E H N R V C D V L K Q E Q G E W D D E R L F R R S R L I L I G E T I K I V I E D Y V R H L S G Y H F S L K F D P E L L F N Q Q F Q Y Q N R I A A E F N T L Y H W H P L L P D T L Q I D D Q E Y N F Q Q F V Y N N S I L L E H G L T Q F G E S F S R Q I A G R V A G G R N V P A A V Q Q E Q R A S I D Q S R Q M K Y Q S L N E Y R K R F S V K P Y A S F E E L T G E K E M A G E L K A L Y Q D I D A M E L Y P A L L V E K P R P D A I F G E T M V E I G A P F S L K G L M G N P I C S P D Y W K P S H F G G E V G F K I I N T A S I Q S L I C N N V K G C P F T A F S V Q D P Q L T K T V T I N G S S S H S G L D D I N P T V L L K E R S T E L
Cofactor	COFACTOR: Name=heme b; Xref=ChEBI:CHEBI:60344; Evidence={ECO:0000250|UniProtKB:Q05769}; Note=Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit. {ECO:0000250|UniProtKB:Q05769};
Active site	ACT_SITE 193 193 Proton acceptor. {ECO:0000255|PROSITE-ProRule:PRU00298}.; ACT_SITE 371 371 For cyclooxygenase activity. {ECO:0000250|UniProtKB:Q05769}.
Pfam	PF03098 PF00008
InterPro	IPR029576 IPR000742 IPR019791 IPR010255 IPR037120