Uniprot ID	O66679
Uniprot Name	RIBBA_AQUAE
Taxonomy ID	224324
Sequence	M S E R E E F K F N T V E E A I E D I R Q G K M V I V V D D P D R E N E G D L V M A A E K V T P E A I N F M A K Y G R G L I C L S L T P E R C E Q L D L H P M T P M N T D P K G T Y F C V S I D A H P K H G T T T G I S A Y D R A L T I K L A I S P D A K P S D F V R P G H V F P L K A R P G G V L E R A G H T E A S V D L A R L A G L Y P A G V I C E I M K D D G T M A R V P D L M E F A K K H N L K I I T I A D L I K Y R L R R E T L V E K V A S A H L P T P W G V F K I H A Y R H K L T G E E Q V A L T M G E W K E D E P V L V R V H S E C L T G D V F R S F R C D C R P Q L E K A L E M I A K E G K G V L V Y I L G H E G R G I G I A N K I K A Y E L Q E K G Y D T V E A N E K L G Y P P D L R D Y G I G A Q I L R D L G V R K M K L M T N N P R K I V A L E G F G L E V V E R V P I K I E P N P Y N K I Y L Q V K K D K L G H M F
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000255|HAMAP-Rule:MF_01283}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000255|HAMAP-Rule:MF_01283}; Note=Binds 2 divalent metal cations per subunit. Magnesium or manganese. {ECO:0000255|HAMAP-Rule:MF_01283}; COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000255|HAMAP-Rule:MF_01283}; Note=Binds 1 zinc ion per subunit. {ECO:0000255|HAMAP-Rule:MF_01283};
Active site	ACT_SITE 338 338 Proton acceptor; for GTP cyclohydrolase activity. {ECO:0000255|HAMAP-Rule:MF_01283}.; ACT_SITE 340 340 Nucleophile; for GTP cyclohydrolase activity. {ECO:0000255|HAMAP-Rule:MF_01283}.
Pfam	PF00926 PF00925
InterPro	IPR017945 IPR000422 IPR032677 IPR000926 IPR036144 IPR016299