Uniprot ID	O66990
Uniprot Name	PYRC_AQUAE
Taxonomy ID	224324
Sequence	M L K L I V K N G Y V I D P S Q N L E G E F D I L V E N G K I K K I D K N I L V P E A E I I D A K G L I V C P G F I D I H V H L R D P G Q T Y K E D I E S G S R C A V A G G F T T I V C M P N T N P P I D N T T V V N Y I L Q K S K S V G L C R V L P T G T I T K G R K G K E I A D F Y S L K E A G C V A F T D D G S P V M D S S V M R K A L E L A S Q L G V P I M D H C E D D K L A Y G V I N E G E V S A L L G L S S R A P E A E E I Q I A R D G I L A Q R T G G H V H I Q H V S T K L S L E I I E F F K E K G V K I T C E V N P N H L L F T E R E V L N S G A N A R V N P P L R K K E D R L A L I E G V K R G I I D C F A T D H A P H Q T F E K E L V E F A M P G I I G L Q T A L P S A L E L Y R K G I I S L K K L I E M F T I N P A R I I G V D L G T L K L G S P A D I T I F D P N K E W I L N E E T N L S K S R N T P L W G K V L K G K V I Y T I K D G K M V Y K D
Cofactor	COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000255|HAMAP-Rule:MF_00220, ECO:0000269|PubMed:15381710, ECO:0000269|PubMed:15826652, ECO:0000269|PubMed:19128030, ECO:0000269|PubMed:24314009}; Note=Binds 1 Zn(2+) ion per subunit (PubMed:15381710, PubMed:15826652, PubMed:19128030, PubMed:24314009). Fully functional with a mononuclear metal center. Does not require a second metal for activity, although the conservation of the second metal-binding site during evolution leaves open the possibility that a second ion might bind in vivo (PubMed:24314009). {ECO:0000269|PubMed:15381710, ECO:0000269|PubMed:15826652, ECO:0000269|PubMed:19128030, ECO:0000269|PubMed:24314009};
Active site	ACT_SITE 305 305 {ECO:0000255|HAMAP-Rule:MF_00220}.
Pfam	PF01979
InterPro	IPR006680 IPR004722 IPR002195 IPR011059 IPR032466