Uniprot ID	O67108
Uniprot Name	TOP4A_AQUAE
Taxonomy ID	224324
Sequence	M E N R E N L V E I P I E E E V K Q A Y I D Y A M S V I V G R A I P D V R D G L K P V Q R R I L Y S M Y E M G L L P D K P F K K S A R I V G E T L G K Y H P H G D Q A V Y E A L V R M A Q D F T M R Y P L I I G Q G N F G S I D G D P A A Q M R Y T E A K L S P L A V E M L T D I D K D T V D F Q P N F D D T L M E P E V L P S K F P N L L C N G T S G I A V G L A T S I P P H N L T E V G N A L V K L A Q N P Q I S V D E I M E I L K G P D F P T G G V I E N F A Q V K E I Y K T G R G I I K V K G K A H V E K V Q G G R E R I V I T E I P Y Q V N K A E L I K K I A D N V R N G K I K E I S D I R D E T D K E G I R I V V E L K R D A K G E E V L K K L Y K Y T P L E K G F P V N L V V L I D K E P K L V D I K T L L R E F I K H R L E V I L R R S K Y F L K K V Q D R L H I V E G L L K A I N F I D D I I E R I R R S K D A S E A R N Y L M E E F G L S E K Q A Q A V L D L R L Q R L T S L E R E K L L E E E K E L R E K I E Y Y K K L V A S E G E R I K V F I E E T E E L V K K Y G D K R R T F I G G V K E V K E G S I T V A V L Q D G S I I P V E E L P L E K A P V V N I L R V P F T E G L F L V S N R G R V Y W I A G S Q A L Q G S K V S L K S R E E K I V G A F I R E K F G N R L L L A T K K G Y V K K I P L A E F E Y K A Q G M P I I K L T E G D E V V S I A S S V D E T H I L L F T K K G R V A R F S V R E V P P S T P G A R G V Q G I K L E K N D E T S G L R I W N G E P Y L L V I T A K G R V K K I S H E E I P K T N R G V K G T E V S G T K D T L V D L I P I K E E V E L L I T T K N G K A F Y D K I N Q K D I P L S T K K S I P R T R W K L E D D E I I K V V I K K S E
Cofactor	No current data
Active site	ACT_SITE 121 121 O-(5'-phospho-DNA)-tyrosine intermediate. {ECO:0000250|UniProtKB:P0AES4}.
Pfam	PF03989 PF00521
InterPro	IPR006691 IPR035516 IPR013760 IPR002205 IPR013758 IPR013757