Uniprot ID	O70628
Uniprot Name	PDE9A_MOUSE
Taxonomy ID	10090
Sequence	M G A G S S S Y R P K A I Y L D I D G R I Q K V V F S K Y C N S S D I M D L F C I A T G L P R N T T I S L L T T D D A M V S I D P T M P A N S E R T P Y K V R P V A V K Q V S E R E E L I Q G V L A Q V A E Q F S R A F K I N E L K A E V A N H L A V L E K R V E L E G L K V V E I E K C K S D I K K M R E E L A A R N S R T N C P C K Y S F L D N K K L T P R R D V P T Y P K Y L L S P E T I E A L R K P T F D V W L W E P N E M L S C L E H M Y H D L G L V R D F S I N P I T L R R W L L C V H D N Y R N N P F H N F R H C F C V T Q M M Y S M V W L C G L Q E K F S Q M D I L V L M T A A I C H D L D H P G Y N N T Y Q I N A R T E L A V R Y N D I S P L E N H H C A I A F Q I L A R P E C N I F A S V P P E G F R Q I R Q G M I T L I L A T D M A R H A E I M D S F K E K M E N F D Y S N E E H L T L L K M I L I K C C D I S N E V R P M E V A E P W V D C L L E E Y F M Q S D R E K S E G L P V A P F M D R D K V T K A T A Q I G F I K F V L I P M F E T V T K L F P V V E E T M L R P L W E S R E H Y E E L K Q L D D A M K E L Q K K T E S L T S G A P E N T T E K N R D A K D S E G H S P P N
Cofactor	COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250|UniProtKB:O76083}; Note=Binds 1 Zn(2+) ion per subunit. Binds 2 divalent metal cations per subunit: site 1 preferentially binds zinc, while site 2 has a preference for magnesium. Tightly binds zinc. {ECO:0000250|UniProtKB:O76083}; COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250|UniProtKB:O76083}; Note=Binds 1 Mg(2+) ions per subunit. Binds 2 divalent metal cations per subunit: site 1 preferentially binds zinc, while site 2 has a preference for magnesium. Binds magnesium less tightly than zinc. {ECO:0000250|UniProtKB:O76083};
Active site	ACT_SITE 251 251 Proton donor. {ECO:0000250|UniProtKB:O76083}.
Pfam	PF00233
InterPro	IPR003607 IPR023088 IPR002073 IPR036971 IPR023174