Uniprot ID	O75106
Uniprot Name	AOC2_HUMAN
Taxonomy ID	9606
Sequence	M H L K I V L A F L A L S L I T I F A L A Y V L L T S P G G S S Q P P H C P S V S H R A Q P W P H P G Q S Q L F A D L S R E E L T A V M R F L T Q R L G P G L V D A A Q A Q P S D N C I F S V E L Q L P P K A A A L A H L D R G S P P P A R E A L A I V L F G G Q P Q P N V S E L V V G P L P H P S Y M R D V T V E R H G G P L P Y H R R P V L R A E F T Q M W R H L K E V E L P K A P I F L S S T F N Y N G S T L A A V H A T P R G L R S G D R A T W M A L Y H N I S G V G L F L H P V G L E L L L D H R A L D P A H W T V Q Q V F Y L G H Y Y A D L G Q L E R E F K S G R L E V V R V P L P P P N G A S S L R S R N S P G P L P P L Q F S P Q G S Q Y S V Q G N L V V S S L W S F T F G H G V F S G L R I F D V R F Q G E R I A Y E V S V Q E C V S I Y G A D S P K T M L T R Y L D S S F G L G R N S R G L V R G V D C P Y Q A T M V D I H I L V G K G A V Q L L P G A V C V F E E A Q G L P L R R H H N Y L Q N H F Y G G L A S S A L V V R S V S S V G N Y D Y I W D F V L Y P N G A L E G R V H A T G Y I N T A F L K G G E E G L L F G N R V G E R V L G T V H T H A F H F K L D L D V A G L K N W V V A E D V V F K P V A A P W N P E H W L Q R P Q L T R Q V L G K E D L T A F S L G S P L P R Y L Y L A S N Q T N A W G H Q R G Y R I Q I H S P L G I H I P L E S D M E R A L S W G R Y Q L V V T Q R K E E E S Q S S S I Y H Q N D I W T P T V T F A D F I N N E T L L G E D L V A W V T A S F L H I P H A E D I P N T V T L G N R V G F L L R P Y N F F D E D P S I F S P G S V Y F E K G Q D A G L C S I N P V A C L P D L A A C V P D L P P F S Y H G F
Cofactor	COFACTOR: Name=Cu cation; Xref=ChEBI:CHEBI:23378; Evidence={ECO:0000250|UniProtKB:P19801}; Note=Binds 1 copper ion per subunit. {ECO:0000250|UniProtKB:P19801}; COFACTOR: Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250|UniProtKB:P19801}; Note=Binds 2 calcium ions per subunit. {ECO:0000250|UniProtKB:P19801}; COFACTOR: Name=L-topaquinone; Xref=ChEBI:CHEBI:79027; Evidence={ECO:0000250|UniProtKB:P19801}; Note=Contains 1 topaquinone per subunit. {ECO:0000250|UniProtKB:P19801};
Active site	ACT_SITE 380 380 Proton acceptor. {ECO:0000250|UniProtKB:P19801}.; ACT_SITE 465 465 Schiff-base intermediate with substrate; via topaquinone. {ECO:0000250|UniProtKB:P19801}.
Pfam	PF01179 PF02727 PF02728
InterPro	IPR032952 IPR000269 IPR015798 IPR036460 IPR016182 IPR015800 IPR015802