Uniprot ID	O83571
Uniprot Name	TKT_TREPA
Taxonomy ID	243276
Sequence	M T E E A M R A M A L S I R S L T I D A I E R A N S G H P G L P L G A A E L A A C L Y G T I L K H N P A N P S W F N R D R F V L S A G H G S M L L Y A A L H L S G Y D V S L E D I K N F R Q V G S R C P G H P E Y G C T P G V E A T T G P L G Q G I S M A V G F A L A E A M L A A R F N T D E H A V V D H H T Y A L V G E G C L M E G V A S E A S S F A G T M R L G K L I V F Y D E N H I S I D G S T D L T F S E D V A K R Y E A Y G W Q V L R G S M Y S Y T D I M D L T A C A K R D D R P S L I I L R S I I G K G A P T V E G S A R A H G A P L G E A G V R E A K K A L G L D P A C S F F V A P E L T A V L Q K R K C E C A H V E D S W N E L F E A W S T Q Y P E K R A D W D A A F V P G G V S T S Q L A R V V C P H F E K G S S L A T R T A S G K V L D A L C S V L P N L V G G S A D L R G P N A V A V S S L R P F S A E H R A G G Y C Y F G V R E F A M A A I V N G M Q L H G G L R A F G A T F M V F S D Y F R P A L R L A A L M R I P S V F V L T H D S I F V G E D G P T H Q P V E T L A A L R A I P N V L V L R P A D A E E T F E A W K I A L L H R S G P V C I V L S R Q N V P V F E K S D S S W R S T V E E S G A Y V V R E G G A T P E L T V L A S G S E V D L A L R A A Q L S K R R V R V V S V L C K E R F E A A G D E V Q R R I Q G G A R V V V A E A G V Y Q G W G A W A K R E K C L V L D R F G X S G P G T Q V A Q A L E F T A E A L V E I I L D W L A
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000250}; Note=Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+). {ECO:0000250}; COFACTOR: Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937; Evidence={ECO:0000250}; Note=Binds 1 thiamine pyrophosphate per subunit. {ECO:0000250};
Active site	ACT_SITE 412 412 Proton donor. {ECO:0000250}.
Pfam	PF02779 PF00456
InterPro	IPR029061 IPR009014 IPR005475 IPR005478 IPR020826 IPR033247 IPR005474