Uniprot ID	O93209
Uniprot Name	POL_FFV
Taxonomy ID	53182
Sequence	M D L L K P L T V E R K G V K I K G Y W D S Q A D I T C V P K D L L Q G E E P V R Q Q N V T T I H G T Q E G D V Y Y V N L K I D G R R I N T E V I G T T L D Y A I I T P G D V P W I L K K P L E L T I K L D L E E Q Q G T L L N N S I L S K K G K E E L K Q L F E K Y S A L W Q S W E N Q V G H R R I R P H K I A T G T V K P T P Q K Q Y H I N P K A K P D I Q I V I N D L L K Q G V L I Q K E S T M N T P V Y P V P K P N G R W R M V L D Y R A V N K V T P L I A V Q N Q H S Y G I L G S L F K G R Y K T T I D L S N G F W A H P I V P E D Y W I T A F T W Q G K Q Y C W T V L P Q G F L N S P G L F T G D V V D L L Q G I P N V E V Y V D D V Y I S H D S E K E H L E Y L D I L F N R L K E A G Y I I S L K K S N I A N S I V D F L G F Q I T N E G R G L T D T F K E K L E N I T A P T T L K Q L Q S I L G L L N F A R N F I P D F T E L I A P L Y A L I P K S T K N Y V P W Q I E H S T T L E T L I T K L N G A E Y L Q G R K G D K T L I M K V N A S Y T T G Y I R Y Y N E G E K K P I S Y V S I V F S K T E L K F T E L E K L L T T V H K G L L K A L D L S M G Q N I H V Y S P I V S M Q N I Q K T P Q T A K K A L A S R W L S W L S Y L E D P R I R F F Y D P Q M P A L K D L P A V D T G K D N K K H P S N F Q H I F Y T D G S A I T S P T K E G H L N A G M G I V Y F I N K D G N L Q K Q Q E W S I S L G N H T A Q F A E I A A F E F A L K K C L P L G G N I L V V T D S N Y V A K A Y N E E L D V W A S N G F V N N R K K P L K H I S K W K S V A D L K R L R P D V V V T H E P G H Q K L D S S P H A Y G N N L A D Q L A T Q A S F K V H M T K N P K L D I E Q I K A I Q A C Q N N E R L P V G Y P K Q Y T Y E L Q N N K C M V L R K D G W R E I P P S R E R Y K L I K E A H N I S H A G R E A V L L K I Q E N Y W W P K M K K D I S S F L S T C N V C K M V N P L N L K P I S P Q A I V H P T K P F D K F Y M D Y I G P L P P S E G Y V H V L V V V D A A T G F T W L Y P T K A Q T S K A T I K V L N H L T G L A I P K V L H S D Q G S A F T S E E F A Q W A K E R N I Q L E F S T P Y H P Q S S G K V E R K N S E I K K L L T K L L V G R P L K W Y N L I S S V Q L A L N N T H V V S T K Y T P H Q L M F G I D C N L P F A N K D T L D W T R E E E L A L L Q E I R E S L Q H P V Q P P T C S G W S P Y V G Q L V Q E R V Y R P S Q L R P K W R K P T K V L E I L N P R T V I I V D H L G Q R K S V S I D N L K P T A H Q H N G T R T C D D P E G M D G M E C S Q T T T E T S V D S S
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 2 magnesium ions for reverse transcriptase polymerase activity. {ECO:0000250}; COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 2 magnesium ions for ribonuclease H (RNase H) activity. Substrate-binding is a precondition for magnesium binding. {ECO:0000250}; COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Magnesium ions are required for integrase activity. Binds at least 1, maybe 2 magnesium ions. {ECO:0000250};
Active site	ACT_SITE 21 21 For protease activity. {ECO:0000255|PROSITE-ProRule:PRU00863}.
Pfam	PF17921 PF00075 PF00665 PF00078 PF18103 PF03539
InterPro	IPR001584 IPR041588 IPR021109 IPR012337 IPR002156 IPR036397 IPR000477 IPR040903 IPR001641