Uniprot ID	O93530
Uniprot Name	WRN_XENLA
Taxonomy ID	8355
Sequence	M T S L Q R K L P E W M S V K Q Q E D R I D D A K K S F C K K N I L E D N L P F M K F N G S I V Y S Y E S N D C S L L S E D I R S S L L E E D V L G F D I E W P P V Y T K G K T G K V A L I Q V C V S E K K C Y L F H I S P M A G F P K G L K R L L E D E S V R K V G V G I E G D Q W K L M S D Y E L K L K G F I E L S E M A N Q K L R C K E K W T F N G L I K H L F K E Q L Y K R K S Y R C S N W D I F L L T E D Q K L Y A A T D A Y A G L L I Y K K L E G M D A H E S D S F R V G R E G V A D C K G V K R Q L T D L S K G L M D L V N Q V P N S F G C Y T E A V R A V D I L E D L S E K L E E L R N I M K E A S K A E G N G L H F Q N S E D C S K K D K S I L H V A C K E S L A E H K M D C K N A D S Q N N K D I D S C Q N E N R D E D F F M T L G I S E E E L Y M M E R E D D K K Q T N P D Y K L N K D S C D T N E E K D M S Y V I E S D E D F D S E I I K S L E D L D N S T E E A L G T G V P Q A G L I P A K S V D T V A D E E E D E G I E E E D D D D D W D P S M P E P S A Q H I S C L K T Y F G H S S F K P V Q W K V V H S V L R E R R D N L V V M A T G Y G K S L C Y Q F A P V Y T S G I G I V I C P L I S L M E D Q V L Q L E M S N I S S C F L G S A Q S K N V L Q D V K D G K M R V I Y M T P E F C S R G I S L L Q D L D N R Y G I T L I A I D E A H C I S E W G H D F R S A Y R S L G S L K R M L P N V P I V A L T A T A S P S I R E D I T K S L N L H N P Q V T C T S F D R P N L Y L D V A R K T T N I S I D L R Q F L I K K Q Q G S G W E F E G A T I V Y C P T R K T S E Q V T A E L I K L G I A C G T Y H A G M G I K Q R R E V H H R F M R D E I H C V V A T V A F G M G I N K P D I R K V I H Y G A P K E M E S Y Y Q E I G R A G R D G L P S C C H A L W A Q A D M N F N R H M L G E I P N K G F R E Y K L K M L T K M E K Y L N S S T C R R K I I L S H F E D K Q L R K A S S G I M G T E K C C D N C K T R L I C N I S I N D T E D N L Q D F G P Q A Y K F I S A V D V L G Q K F G T G V P V L F L R G S T S Q R V P D R F R N H S L F S S G K D Q T E A F W K V L A R Q L I T E G Y L Q E S S G Q T K F S T I C G L T S K G S N W L I K A N N E Q C P S L L L P S N N E L C L Q R T R V S N F S S A Q A H S S M V P H A S S N T R S S M P K A G P E K M E L K D K F S Y Q E A E R L S K A A G V S K S S F K L Q T P C K L S R P P E P E V S P R E R E L Q T T L Y G R L V V A R Q K I A S E R D I L P A V L A T N K V L V D M A K L R P T T S E N M K K L D G V S E A K S A M L A P L L E V V K E F C I A N S L K V D V F S G S V S Q S E S T F F T P R E Q E R I S L P E S Q R M S Y S L F Q E Q N L S L K K I A D V R C L S M A V V G M H L W Q A L K A G Y S F D V Q R A G L T P E M K K L I T Y A I K K P P I N S D L S S F K A I R E Y V P A N I D G Y P I R M V I S L L E K E G S S G A Q G Q P E F P T Q K T L I Q T E E N P K N V S V Q N T K H K V T M G K S M W I E K K P T Q P A T A E L E V T K G K A L A P I M L A S W N E A S L D A D T E E L F S E S Q S S T T R P R R R L P E W F G S T K G N A A T R C I Q E S K N L G E E K G S F F D
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250|UniProtKB:Q14191}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250|UniProtKB:Q14191}; Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250|UniProtKB:Q14191}; Note=Binds 2 magnesium ions per subunit. Has high activity with manganese and zinc ions (in vitro). {ECO:0000250|UniProtKB:Q14191};
Active site	No current data
Pfam	PF00270 PF01612 PF00271 PF00570 PF14493 PF16124 PF09382
InterPro	IPR002562 IPR011545 IPR004589 IPR014001 IPR001650 IPR029491 IPR010997 IPR002121 IPR027417 IPR032284 IPR012337 IPR036397 IPR018982 IPR036388 IPR036390