Uniprot ID	P0A621
Uniprot Name	TOP1_MYCBO
Taxonomy ID	233413
Sequence	M A D P K T K G R G S G G N G S G R R L V I V E S P T K A R K L A S Y L G S G Y I V E S S R G H I R D L P R A A S D V P A K Y K S Q P W A R L G V N V D A D F E P L Y I I S P E K R S T V S E L R G L L K D V D E L Y L A T D G D R E G E A I A W H L L E T L K P R I P V K R M V F H E I T E P A I R A A A E H P R D L D I D L V D A Q E T R R I L D R L Y G Y E V S P V L W K K V A P K L S A G R V Q S V A T R I I V A R E R D R M A F R S A A Y W D I L A K L D A S V S D P D A A P P T F S A R L T A V A G R R V A T G R D F D S L G T L R K G D E V I V L D E G S A T A L A A G L D G T Q L T V A S A E E K P Y A R R P Y P P F M T S T L Q Q E A S R K L R F S A E R T M S I A Q R L Y E N G Y I T Y M R T D S T T L S E S A I N A A R T Q A R Q L Y G D E Y V A P A P R Q Y T R K V K N A Q E A H E A I R P A G E T F A T P D A V R R E L D G P N I D D F R L Y E L I W Q R T V A S Q M A D A R G M T L S L R I T G M S G H Q E V V F S A T G R T L T F P G F L K A Y V E T V D E L V G G E A D D A E R R L P H L T P G Q R L D I V E L T P D G H A T N P P A R Y T E A S L V K A L E E L G I G R P S T Y S S I I K T I Q D R G Y V H K K G S A L V P S W V A F A V T G L L E Q H F G R L V D Y D F T A A M E D E L D E I A A G N E R R T N W L N N F Y F G G D H G V P D S V A R S G G L K K L V G I N L E G I D A R E V N S I K L F D D T H G R P I Y V R V G K N G P Y L E R L V A G D T G E P T P Q R A N L S D S I T P D E L T L Q V A E E L F A T P Q Q G R T L G L D P E T G H E I V A R E G R F G P Y V T E I L P E P A A D A A A A A Q G V K K R Q K A A G P K P R T G S L L R S M D L Q T V T L E D A L R L L S L P R V V G V D P A S G E E I T A Q N G R Y G P Y L K R G N D S R S L V T E D Q I F T I T L D E A L K I Y A E P K R R G R Q S A S A P P L R E L G T D P A S G K P M V I K D G R F G P Y V T D G E T N A S L R K G D D V A S I T D E R A A E L L A D R R A R G P A K R P A R K A A R K V P A K K A A K R D
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000255|HAMAP-Rule:MF_00952}; Note=Binds two Mg(2+) per subunit. {ECO:0000255|HAMAP-Rule:MF_00952};
Active site	ACT_SITE 342 342 O-(5'-phospho-DNA)-tyrosine intermediate. {ECO:0000255|HAMAP-Rule:MF_00952}.
Pfam	PF01131 PF01751 PF13368
InterPro	IPR000380 IPR003601 IPR023406 IPR013497 IPR013824 IPR013825 IPR013826 IPR023405 IPR003602 IPR005733 IPR028612 IPR025589 IPR006171 IPR034149