Uniprot ID	P0C7P3
Uniprot Name	SLN14_HUMAN
Taxonomy ID	9606
Sequence	M E S L K T D T E M P Y P E V I V D V G R V I F G E E N R K K M T N S C L K R S E N S R I I R A I C A L L N S G G G V I K A E I D D K T Y S Y Q C H G L G Q D L E T S F Q K L L P S G S Q K Y L D Y M Q Q G H N L L I F V K S W S P D V F S L P L R I C S L R S N L Y R R D V T S A I N L S A S S A L E L L R E K G F R A Q R G R P R V K K L H P Q Q V L N R C I Q E E E D M R I L A S E F F K K D K L M Y K E K L N F T E S T H V E F K R F T T K K V I P R I K E M L P H Y V S A F A N T Q G G Y V L I G V D D K S K E V V G C K W E K V N P D L L K K E I E N C I E K L P T F H F C C E K P K V N F T T K I L N V Y Q K D V L D G Y V C V I Q V E P F C C V V F A E A P D S W I M K D N S V T R L T A E Q W V V M M L D T Q S A P P S L V T D Y N S C L I S S A S S A R K S P G Y P I K V H K F K E A L Q R H L F P V T Q E E V Q F K P E S L C K K L F S D H K E L E G L M K T L I H P C S Q G I V I F S R S W A G D V G F R K E Q N V L C D A L L I A V N S P V V L Y T I L I D P N W P G G L E Y A R N T A H Q L K Q K L Q T V G G Y T G K V C I I P R L I H L S S T Q S R P G E I P L R Y P R S Y R L A D E E E M E D L L Q A L V V V S L S S R S L L S D Q M G C E F F N L L I M E Q S Q L L S E S L Q K T R E L F I Y C F P G V R K T A L A I K I M E K I K D L F H C K P K E I L Y V C E S D S L K D F V T Q Q T T C Q A V T R K T F M Q G E F L K I K H I V M D E T E N F C S K Y G N W Y M K A K N I T H P K A K G T G S E N L H H G I L W L F L D P F Q I H H A D V N G L P P P S A Q F P R K T I T S G I H C A L E I A K V M K E E M K R I K E N P P S N M S P D T L A L F S E T A Y E E A T C A Q A L P G V C E T K T N L T T E Q I A N Y V A R K C H S L F Q C G Y L P K D I A I L C R R G E D R G R Y R L A L L K A M E L I E T H R P S E V V F S P A T G V W G S H I V L D S I Q Q F S G L E R T V V F G L S P E C D Q S E E F H K L C F A S R A I K H L Y L L Y E K R A A Y
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250|UniProtKB:G1SRW8}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250|UniProtKB:G1SRW8}; Note=C-terminally truncated SLFN14 endoribonuclease requires manganese and magnesium for its endoribonuclease activity. {ECO:0000250|UniProtKB:G1SRW8};
Active site	No current data
Pfam	PF04326
InterPro	IPR027417 IPR029684 IPR007421 IPR038461 IPR029677