Uniprot ID	P0DPD6
Uniprot Name	ECE2_HUMAN
Taxonomy ID	9606
Sequence	M N V A L Q E L G A G S N M V E Y K R A T L R D E D A P E T P V E G G A S P D A M E V G K G A S P F S P G P S P G M T P G T P R S S G L F W R V T C P H L R S I S G L C S R T M V G F Q K G T R Q L L G S R T Q L E L V L A G A S L L L A A L L L G C L V A L G V Q Y H R D P S H S T C L T E A C I R V A G K I L E S L D R G V S P C E D F Y Q F S C G G W I R R N P L P D G R S R W N T F N S L W D Q N Q A I L K H L L E N T T F N S S S E A E Q K T Q R F Y L S C L Q V E R I E E L G A Q P L R D L I E K I G G W N I T G P W D Q D N F M E V L K A V A G T Y R A T P F F T V Y I S A D S K S S N S N V I Q V D Q S G L F L P S R D Y Y L N R T A N E K V L T A Y L D Y M E E L G M L L G G R P T S T R E Q M Q Q V L E L E I Q L A N I T V P Q D Q R R D E E K I Y H K M S I S E L Q A L A P S M D W L E F L S F L L S P L E L S D S E P V V V Y G M D Y L Q Q V S E L I N R T E P S I L N N Y L I W N L V Q K T T S S L D R R F E S A Q E K L L E T L Y G T K K S C V P R W Q T C I S N T D D A L G F A L G S L F V K A T F D R Q S K E I A E G M I S E I R T A F E E A L G Q L V W M D E K T R Q A A K E K A D A I Y D M I G F P D F I L E P K E L D D V Y D G Y E I S E D S F F Q N M L N L Y N F S A K V M A D Q L R K P P S R D Q W S M T P Q T V N A Y Y L P T K N E I V F P A G I L Q A P F Y A R N H P K A L N F G G I G V V M G H E L T H A F D D Q G R E Y D K E G N L R P W W Q N E S L A A F R N H T A C M E E Q Y N Q Y Q V N G E R L N G R Q T L G E N I A D N G G L K A A Y N A Y K A W L R K H G E E Q Q L P A V G L T N H Q L F F V G F A Q V W C S V R T P E S S H E G L V T D P H S P A R F R V L G T L S N S R D F L R H F G C P V G S P M N P G Q L C E V W
Cofactor	COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250|UniProtKB:P42892}; Note=Binds 1 zinc ion per subunit. {ECO:0000250|UniProtKB:P42892};
Active site	ACT_SITE 649 649 {ECO:0000255|PROSITE-ProRule:PRU01233, ECO:0000255|PROSITE-ProRule:PRU10095}.; ACT_SITE 712 712 Proton donor. {ECO:0000255|PROSITE-ProRule:PRU01233}.
Pfam	PF01431 PF05649
InterPro	IPR024079 IPR000718 IPR018497 IPR042089 IPR008753