Uniprot ID	P11678
Uniprot Name	PERE_HUMAN
Taxonomy ID	9606
Sequence	M H L L P A L A G V L A T L V L A Q P C E G T D P A S P G A V E T S V L R D C I A E A K L L V D A A Y N W T Q K S I K Q R L R S G S A S P M D L L S Y F K Q P V A A T R T V V R A A D Y M H V A L G L L E E K L Q P Q R S G P F N V T D V L T E P Q L R L L S Q A S G C A L R D Q A E R C S D K Y R T I T G R C N N K R R P L L G A S N Q A L A R W L P A E Y E D G L S L P F G W T P S R R R N G F L L P L V R A V S N Q I V R F P N E R L T S D R G R A L M F M Q W G Q F I D H D L D F S P E S P A R V A F T A G V D C E R T C A Q L P P C F P I K I P P N D P R I K N Q R D C I P F F R S A P S C P Q N K N R V R N Q I N A L T S F V D A S M V Y G S E V S L S L R L R N R T N Y L G L L A I N Q R F Q D N G R A L L P F D N L H D D P C L L T N R S A R I P C F L A G D T R S T E T P K L A A M H T L F M R E H N R L A T E L R R L N P R W N G D K L Y N E A R K I M G A M V Q I I T Y R D F L P L V L G K A R A R R T L G H Y R G Y C S N V D P R V A N V F T L A F R F G H T M L Q P F M F R L D S Q Y R A S A P N S H V P L S S A F F A S W R I V Y E G G I D P I L R G L M A T P A K L N R Q D A M L V D E L R D R L F R Q V R R I G L D L A A L N M Q R S R D H G L P G Y N A W R R F C G L S Q P R N L A Q L S R V L K N Q D L A R K F L N L Y G T P D N I D I W I G A I A E P L L P G A R V G P L L A C L F E N Q F R R A R D G D R F W W Q K R G V F T K R Q R K A L S R I S L S R I I C D N T G I T T V S R D I F R A N I Y P R G F V N C S R I P R L N L S A W R G T
Cofactor	COFACTOR: Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000255|PROSITE-ProRule:PRU00298}; Note=Binds 1 Ca(2+) ion per heterodimer. {ECO:0000255|PROSITE-ProRule:PRU00298}; COFACTOR: Name=heme b; Xref=ChEBI:CHEBI:60344; Note=Binds 1 heme b (iron(II)-protoporphyrin IX) covalently through ester linkages to hydroxylated methyl groups formed auto-catalytically with hydrogen peroxide at the heme C-1 and C-5 positions. The ester linkage to Asp-232 was observed in 30% of the chains.;
Active site	ACT_SITE 233 233 Proton acceptor. {ECO:0000255|PROSITE-ProRule:PRU00298}.
Pfam	PF03098
InterPro	IPR029599 IPR019791 IPR010255 IPR037120