Uniprot ID	P14270
Uniprot Name	PDE4D_RAT
Taxonomy ID	10116
Sequence	M E A E G S S V P A R A G S H E G S D S S G G A A L K A P K H L W R H E Q H H Q Y P L R Q P Q F R L L H P H H H L P P P P P P S P Q P Q L Q P P P P P P L P P P P P P P G A T R G R Y A S S G A S R V R H R G Y S D T E R Y L Y C R A M D R T S Y A V E T G H R P G L K K S R M S W P S S F Q G L R R F D V D N G T S A G R S P L D P M T S P G S G L I L Q A N F V H S Q R R E S F L Y R S D S D Y D L S P K S M S R N S S I A S D I H G D D L I V T P F A Q V L A S L R T V R N N F A A L T N L Q D R A P S K R S P M C N Q P S I N K A T I T E E A Y Q K L A S E T L E E L D W C L D Q L E T L Q T R H S V S E M A S N K F K R M L N R E L T H L S E M S R S G N Q V S E Y I S N T F L D K Q H E V E I P S P T Q K E K E K K K R P M S Q I S G V K K L M H S S S L T N S C I P R F G V K T E Q E D V L A K E L E D V N K W G L H V F R I A E L S G N R P L T V I M H T I F Q E R D L L K T F K I P V D T L I T Y L M T L E D H Y H A D V A Y H N N I H A A D V V Q S T H V L L S T P A L E A V F T D L E I L A A I F A S A I H D V D H P G V S N Q F L I N T N S E L A L M Y N D S S V L E N H H L A V G F K L L Q E E N C D I F Q N L T K K Q R Q S L R K M A I D I V L A T D M S K H M N L L A D L K T M V E T K K V T S S G V L L L D N Y S D R I Q V L Q N M V H C A D L S N P T K P L Q L Y R Q W T D R I M E E F F R Q G D R E R E R G M E I S P M C D K H N A S V E K S Q V G F I D Y I V H P L W E T W A D L V H P D A Q D I L D T L E D N R E W Y Q S T I P Q S P S P A P D D Q E D G R Q G Q T E K F Q F E L T L E E D G E S D T E K D S G S Q V E E D T S C S D S K T L C T Q D S E S T E I P L D E Q V E E E A V A E E E S Q P Q T G V A D D C C P D T
Cofactor	COFACTOR: Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; Evidence={ECO:0000250}; Note=Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. {ECO:0000250};
Active site	ACT_SITE 457 457 Proton donor. {ECO:0000250}.
Pfam	PF18100 PF00233
InterPro	IPR003607 IPR040844 IPR023088 IPR002073 IPR036971 IPR023174