Uniprot ID	P14902
Uniprot Name	I23O1_HUMAN
Taxonomy ID	9606
Sequence	M A H A M E N S W T I S K E Y H I D E E V G F A L P N P Q E N L P D F Y N D W M F I A K H L P D L I E S G Q L R E R V E K L N M L S I D H L T D H K S Q R L A R L V L G C I T M A Y V W G K G H G D V R K V L P R N I A V P Y C Q L S K K L E L P P I L V Y A D C V L A N W K K K D P N K P L T Y E N M D V L F S F R D G D C S K G F F L V S L L V E I A A A S A I K V I P T V F K A M Q M Q E R D T L L K A L L E I A S C L E K A L Q V F H Q I H D H V N P K A F F S V L R I Y L S G W K G N P Q L S D G L V Y E G F W E D P K E F A G G S A G Q S S V F Q C F D V L L G I Q Q T A G G G H A A Q F L Q D M R R Y M P P A H R N F L C S L E S N P S V R E F V L S K G D A G L R E A Y D A C V K A L V S L R S Y H L Q I V T K Y I L I P A S Q Q P K E N K T S E D P S K L E A K G T G G T D L M N F L K T V R S T T E K S L L K E G
Cofactor	COFACTOR: Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000269|PubMed:16477023, ECO:0000269|PubMed:25313323}; Note=Binds 1 heme group per subunit (PubMed:16477023, PubMed:25313323). In the active form, the heme iron is in its ferrous state Fe(+2). The catalytic cycle does not alter the oxidation state of the heme, but IDO1 is prone to autoxidation (PubMed:16574111). {ECO:0000269|PubMed:16477023, ECO:0000269|PubMed:16574111, ECO:0000269|PubMed:25313323};
Active site	No current data
Pfam	PF01231
InterPro	IPR000898 IPR037217