Uniprot ID	P22147
Uniprot Name	XRN1_YEAST
Taxonomy ID	559292
Sequence	M G I P K F F R Y I S E R W P M I L Q L I E G T Q I P E F D N L Y L D M N S I L H N C T H G N D D D V T K R L T E E E V F A K I C T Y I D H L F Q T I K P K K I F Y M A I D G V A P R A K M N Q Q R A R R F R T A M D A E K A L K K A I E N G D E I P K G E P F D S N S I T P G T E F M A K L T K N L Q Y F I H D K I S N D S K W R E V Q I I F S G H E V P G E G E H K I M N F I R H L K S Q K D F N Q N T R H C I Y G L D A D L I M L G L S T H G P H F A L L R E E V T F G R R N S E K K S L E H Q N F Y L L H L S L L R E Y M E L E F K E I A D E M Q F E Y N F E R I L D D F I L V M F V I G N D F L P N L P D L H L N K G A F P V L L Q T F K E A L L H T D G Y I N E H G K I N L K R L G V W L N Y L S Q F E L L N F E K D D I D V E W F N K Q L E N I S L E G E R K R Q R V G K K L L V K Q Q K K L I G S I K P W L M E Q L Q E K L S P D L P D E E I P T L E L P K D L D M K D H L E F L K E F A F D L G L F I T H S K S K G S Y S L K M D L D S I N P D E T E E E F Q N R V N S I R K T I K K Y Q N A I I V E D K E E L E T E K T I Y N E R F E R W K H E Y Y H D K L K F T T D S E E K V R D L A K D Y V E G L Q W V L Y Y Y Y R G C P S W S W Y Y P H H Y A P R I S D L A K G L D Q D I E F D L S K P F T P F Q Q L M A V L P E R S K N L I P P A F R P L M Y D E Q S P I H D F Y P A E V Q L D K N G K T A D W E A V V L I S F V D E K R L I E A M Q P Y L R K L S P E E K T R N Q F G K D L I Y S F N P Q V D N L Y K S P L G G I F S D I E H N H C V E K E Y I T I P L D S S E I R Y G L L P N A K L G A E M L A G F P T L L S L P F T S S L E Y N E T M V F Q Q P S K Q Q S M V L Q I T D I Y K T N N V T L E D F S K R H L N K V I Y T R W P Y L R E S K L V S L T D G K T I Y E Y Q E S N D K K K F G F I T K P A E T Q D K K L F N S L K N S M L R M Y A K Q K A V K I G P M E A I A T V F P V T G L V R D S D G G Y I K T F S P T P D Y Y P L Q L V V E S V V N E D E R Y K E R G P I P I E E E F P L N S K V I F L G D Y A Y G G E T T I D G Y S S D R R L K I T V E K K F L D S E P T I G K E R L Q M D H Q A V K Y Y P S Y I V S K N M H L H P L F L S K I T S K F M I T D A T G K H I N V G I P V K F E A R H Q K V L G Y A R R N P R G W E Y S N L T L N L L K E Y R Q T F P D F F F R L S K V G N D I P V L E D L F P D T S T K D A M N L L D G I K Q W L K Y V S S K F I A V S L E S D S L T K T S I A A V E D H I M K Y A A N I E G H E R K Q L A K V P R E A V L N P R S S F A L L R S Q K F D L G D R V V Y I Q D S G K V P I F S K G T V V G Y T T L S S S L S I Q V L F D H E I V A G N N F G G R L R T N R G L G L D A S F L L N I T N R Q F I Y H S K A S K K A L E K K K Q S N N R N N N T K T A H K T P S K Q Q S E E K L R K E R A H D L L N F I K K D T N E K N S E S V D N K S M G S Q K D S K P A K K V L L K R P A Q K S S E N V Q V D L A N F E K A P L D N P T V A G S I F N A V A N Q Y S D G I G S N L N I P T P P H P M N V V G G P I P G A N D V A D V G L P Y N I P P G F M T H P N G L H P L H P H Q M P Y P N M N G M S I P P P A P H G F G Q P I S F P P P P P M T N V S D Q G S R I V V N E K E S Q D L K K F I N G K Q H S N G S T I G G E T K N S R K G E I K P S S G T N S T E C Q S P K S Q S N A A D R D N K K D E S T
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Note=Both strand exchange and nuclease activities require magnesium, for the strand exchange activity, calcium can replace magnesium when the linear ds-DNA has been first resected with an exogenous endonuclease.;
Active site	No current data
Pfam	PF18129 PF18332 PF18334 PF18194 PF17846 PF03159
InterPro	IPR027073 IPR016494 IPR004859 IPR014722 IPR041385 IPR040992 IPR041106 IPR040486 IPR041412