Uniprot ID	P23074
Uniprot Name	POL_SFV1
Taxonomy ID	338478
Sequence	M D P L Q L L Q P L E A E I K G T K L K A H W D S G A T I T C V P E A F L E D E R P I Q T M L I K T I H G E K Q Q D V Y Y L T F K V Q G R K V E A E V L A S P Y D Y I L L N P S D V P W L M K K P L Q L T V L V P L H E Y Q E R L L Q Q T A L P K E Q K E L L Q K L F L K Y D A L W Q H W E N Q V G H R R I K P H N I A T G T L A P R P Q K Q Y P I N P K A K P S I Q I V I D D L L K Q G V L I Q Q N S T M N T P V Y P V P K P D G K W R M V L D Y R E V N K T I P L I A A Q N Q H S A G I L S S I Y R G K Y K T T L D L T N G F W A H P I T P E S Y W L T A F T W Q G K Q Y C W T R L P Q G F L N S P A L F T A D V V D L L K E I P N V Q A Y V D D I Y I S H D D P Q E H L E Q L E K I F S I L L N A G Y V V S L K K S E I A Q R E V E F L G F N I T K E G R G L T D T F K Q K L L N I T P P K D L K Q L Q S I L G L L N F A R N F I P N Y S E L V K P L Y T I V A N A N G K F I S W T E D N S N Q L Q H I I S V L N Q A D N L E E R N P E T R L I I K V N S S P S A G Y I R Y Y N E G S K R P I M Y V N Y I F S K A E A K F T Q T E K L L T T M H K G L I K A M D L A M G Q E I L V Y S P I V S M T K I Q R T P L P E R K A L P V R W I T W M T Y L E D P R I Q F H Y D K S L P E L Q Q I P N V T E D V I A K T K H P S E F A M V F Y T D G S A I K H P D V N K S H S A G M G I A Q V Q F I P E Y K I V H Q W S I P L G D H T A Q L A E I A A V E F A C K K A L K I S G P V L I V T D S F Y V A E S A N K E L P Y W K S N G F L N N K K K P L R H V S K W K S I A E C L Q L K P D I I I M H E K G H Q Q P M T T L H T E G N N L A D K L A T Q G S Y V V H C N T T P S L D A E L D Q L L Q G H Y P P G Y P K Q Y K Y T L E E N K L I V E R P N G I R I V P P K A D R E K I I S T A H N I A H T G R D A T F L K V S S K Y W W P N L R K D V V K S I R Q C K Q C L V T N A T N L T S P P I L R P V K P L K P F D K F Y I D Y I G P L P P S N G Y L H V L V V V D S M T G F V W L Y P T K A P S T S A T V K A L N M L T S I A I P K V L H S D Q G A A F T S S T F A D W A K E K G I Q L E F S T P Y H P Q S S G K V E R K N S D I K R L L T K L L I G R P A K W Y D L L P V V Q L A L N N S Y S P S S K Y T P H Q L L F G V D S N T P F A N S D T L D L S R E E E L S L L Q E I R S S L H Q P T S P P A S S R S W S P S V G Q L V Q E R V A R P A S L R P R W H K P T A I L E V V N P R T V I I L D H L G N R R T V S V D N L K L T A Y Q D N G T S N D S G T M A L M E E D E S S T S S T
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 2 magnesium ions for reverse transcriptase polymerase activity. {ECO:0000250}; COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 2 magnesium ions for ribonuclease H (RNase H) activity. Substrate-binding is a precondition for magnesium binding. {ECO:0000250}; COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Magnesium ions are required for integrase activity. Binds at least 1, maybe 2 magnesium ions. {ECO:0000250};
Active site	ACT_SITE 24 24 For protease activity. {ECO:0000255|PROSITE-ProRule:PRU00863}.
Pfam	PF17921 PF00075 PF17919 PF00665 PF00078 PF18103 PF03539
InterPro	IPR001584 IPR041588 IPR021109 IPR012337 IPR002156 IPR036397 IPR000477 IPR041577 IPR040903 IPR001641