Uniprot ID	P27401
Uniprot Name	POL_SFV3L
Taxonomy ID	11644
Sequence	M D P L Q L L Q P L E A E I K G T K L K A H W D S G A T I T C V P Q A F L E E E V P I K N I W I K T I H G E K E Q P V Y Y L T F K I Q G R K V E A E V I S S P Y D Y I L V S P S D I P W L M K K P L Q L T T L V P L Q E Y E E R L L K Q T M L T G S Y K E K L Q S L F L K Y D A L W Q H W E N Q V G H R R I K P H H I A T G T V N P R P Q K Q Y P I N P K A K A S I Q T V I N D L L K Q G V L I Q Q N S I M N T P V Y P V P K P D G K W R M V L D Y R E V N K T I P L I A A Q N Q H S A G I L S S I F R G K Y K T T L D L S N G F W A H S I T P E S Y W L T A F T W L G Q Q Y C W T R L P Q G F L N S P A L F T A D V V D L L K E V P N V Q V Y V D D I Y I S H D D P R E H L E Q L E K V F S L L L N A G Y V V S L K K S E I A Q H E V E F L G F N I T K E G R G L T E T F K Q K L L N I T P P R D L K Q L Q S I L G L L N F A R N F I P N F S E L V K P L Y N I I A T A N G K Y I T W T T D N S Q Q L Q N I I S M L N S A E N L E E R N P E V R L I M K V N T S P S A G Y I R F Y N E F A K R P I M Y L N Y V Y T K A E V K F T N T E K L L T T I H K G L I K A L D L G M G Q E I L V Y S P I V S M T K I Q K T P L P E R K A L P I R W I T W M S Y L E D P R I Q F H Y D K T L P E L Q Q V P T V T D D I I A K I K H P S E F S M V F Y T D G S A I K H P N V N K S H N A G M G I A Q V Q F K P E F T V I N T W S I P L G D H T A Q L A E V A A V E F A C K K A L K I D G P V L I V T D S F Y V A E S V N K E L P Y W Q S N G F F N N K K K P L K H V S K W K S I A D C I Q L K P D I I I I H E K G H Q P T A S T F H T E G N N L A D K L A T Q G S Y V V N I N T T P S L D A E L D Q L L Q G Q Y P K G F P K H Y Q Y Q L E N G Q V M V T R P N G K R I I P P K S D R P Q I I L Q A H N I A H T G R D S T F L K V S S K Y W W P N L R K D V V K V I R Q C K Q C L V T N A A T L A A P P I L R P E R P V K P F D K F F I D Y I G P L P P S N G Y L H V L V V V D S M T G F V W L Y P T K A P S T S A T V K A L N M L T S I A V P K V I H S D Q G A A F T S A T F A D W A K N K G I Q L E F S T P Y H P Q S S G K V E R K N S D I K R L L T K L L V G R P A K W Y D L L P V V Q L A L N N S Y S P S S K Y T P H Q L L F G I D S N T P F A N S D T L D L S R E E E L S L L Q E I R S S L Y L P S T P P A S I R A W S P S V G Q L V Q E R V A R P A S L R P R W H K P T P V L E V I N P R A V V I L D H L G N R R T V S V D N L K L T A Y Q K D G T P N E S A A V V A M E K D E
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 2 magnesium ions for reverse transcriptase polymerase activity. {ECO:0000250}; COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 2 magnesium ions for ribonuclease H (RNase H) activity. Substrate-binding is a precondition for magnesium binding. {ECO:0000250}; COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Magnesium ions are required for integrase activity. Binds at least 1, maybe 2 magnesium ions. {ECO:0000250};
Active site	ACT_SITE 24 24 For protease activity. {ECO:0000255|PROSITE-ProRule:PRU00863}.
Pfam	PF17921 PF00075 PF00665 PF00078 PF18103 PF03539
InterPro	IPR001584 IPR041588 IPR021109 IPR012337 IPR002156 IPR036397 IPR000477 IPR040903 IPR001641