Uniprot ID	P29277
Uniprot Name	TKT_RHOSH
Taxonomy ID	1063
Sequence	M K D I G A A Q E T R M A N A I R A L A M D A V E K A K S G H P G M P M G M A D V A T V L F N R F L T V D P S A P K W P D R D R F V L S A G H G S M L L Y A I H H L L G Y A D M D M D Q I R S F R Q L G A R T A G H P E Y G H A E G I E V T T G P L G Q G I A T A V G M A L A E R M K N A R Y G D D L V D H F T Y V I A G D G C L M E G I S H E A I D M G G H L G L G R L I V L W D D N R I T I D G D S G I S T S T D Q K A P F A A S G W H V L A C D G H A P E E I A A A I E A A R R D P R P S M I A C R T V I G Y G A P N K Q G G H D V H G A P L G A A E I A A A R E R L G W D H P P F E I P A D L Y E A W G R I A A R G A D A R A A W E T R L Q A S P L R A A F E T A E A A D T S A L P P A I A A Y K A R L S A E A P K V A T R K A S E M A L G V V N E A L P F A V G G S A D L T G S N L T R S K G M V S V A P G A F A G S Y I H Y G I R E H G M A A A M N G I A L H G G L R P Y G G T F M A F A D Y C R P S I R L S A L M G V P V T Y V M T H D S I G L G E D G P T H Q P V E H L A S L R A I P N L A V I R P A D A V E T A E A W E I A M T A T S T P T L L V L S R Q N L P T V R T E H R D E N L T A R G A Y L L R D P G E R Q V T L I A T G S E L E L A L A A A D L L A A E G I A A A V V S A P C F E L F A A Q P A D Y R A T V L G R A P R V G C E A A L R Q G W D L F L G P Q D G F V G M T G F G A S A P A P A L Y Q H F N I T A E A I V K S A K E R I
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000250}; Note=Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+). {ECO:0000250}; COFACTOR: Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937; Evidence={ECO:0000250}; Note=Binds 1 thiamine pyrophosphate per subunit. {ECO:0000250};
Active site	ACT_SITE 408 408 Proton donor. {ECO:0000250}.
Pfam	PF02779 PF02780 PF00456
InterPro	IPR029061 IPR009014 IPR005475 IPR005478 IPR020826 IPR033248 IPR033247 IPR005474