Uniprot ID	P29474
Uniprot Name	NOS3_HUMAN
Taxonomy ID	9606
Sequence	M G N L K S V A Q E P G P P C G L G L G L G L G L C G K Q G P A T P A P E P S R A P A S L L P P A P E H S P P S S P L T Q P P E G P K F P R V K N W E V G S I T Y D T L S A Q A Q Q D G P C T P R R C L G S L V F P R K L Q G R P S P G P P A P E Q L L S Q A R D F I N Q Y Y S S I K R S G S Q A H E Q R L Q E V E A E V A A T G T Y Q L R E S E L V F G A K Q A W R N A P R C V G R I Q W G K L Q V F D A R D C R S A Q E M F T Y I C N H I K Y A T N R G N L R S A I T V F P Q R C P G R G D F R I W N S Q L V R Y A G Y R Q Q D G S V R G D P A N V E I T E L C I Q H G W T P G N G R F D V L P L L L Q A P D D P P E L F L L P P E L V L E V P L E H P T L E W F A A L G L R W Y A L P A V S N M L L E I G G L E F P A A P F S G W Y M S T E I G T R N L C D P H R Y N I L E D V A V C M D L D T R T T S S L W K D K A A V E I N V A V L H S Y Q L A K V T I V D H H A A T A S F M K H L E N E Q K A R G G C P A D W A W I V P P I S G S L T P V F H Q E M V N Y F L S P A F R Y Q P D P W K G S A A K G T G I T R K K T F K E V A N A V K I S A S L M G T V M A K R V K A T I L Y G S E T G R A Q S Y A Q Q L G R L F R K A F D P R V L C M D E Y D V V S L E H E T L V L V V T S T F G N G D P P E N G E S F A A A L M E M S G P Y N S S P R P E Q H K S Y K I R F N S I S C S D P L V S S W R R K R K E S S N T D S A G A L G T L R F C V F G L G S R A Y P H F C A F A R A V D T R L E E L G G E R L L Q L G Q G D E L C G Q E E A F R G W A Q A A F Q A A C E T F C V G E D A K A A A R D I F S P K R S W K R Q R Y R L S A Q A E G L Q L L P G L I H V H R R K M F Q A T I R S V E N L Q S S K S T R A T I L V R L D T G G Q E G L Q Y Q P G D H I G V C P P N R P G L V E A L L S R V E D P P A P T E P V A V E Q L E K G S P G G P P P G W V R D P R L P P C T L R Q A L T F F L D I T S P P S P Q L L R L L S T L A E E P R E Q Q E L E A L S Q D P R R Y E E W K W F R C P T L L E V L E Q F P S V A L P A P L L L T Q L P L L Q P R Y Y S V S S A P S T H P G E I H L T V A V L A Y R T Q D G L G P L H Y G V C S T W L S Q L K P G D P V P C F I R G A P S F R L P P D P S L P C I L V G P G T G I A P F R G F W Q E R L H D I E S K G L Q P T P M T L V F G C R C S Q L D H L Y R D E V Q N A Q Q R G V F G R V L T A F S R E P D N P K T Y V Q D I L R T E L A A E V H R V L C L E R G H M F V C G D V T M A T N V L Q T V Q R I L A T E G D M E L D E A G D V I G V L R D Q Q R Y H E D I F G L T L R T Q E V T S R I R T Q S F S L Q E R Q L R G A V P W A F D P P G S D T N S P
Cofactor	COFACTOR: Name=heme; Xref=ChEBI:CHEBI:30413; ; COFACTOR: Name=FAD; Xref=ChEBI:CHEBI:57692; Note=Binds 1 FAD.; COFACTOR: Name=FMN; Xref=ChEBI:CHEBI:58210; Note=Binds 1 FMN.; COFACTOR: Name=(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin; Xref=ChEBI:CHEBI:59560; Note=Tetrahydrobiopterin (BH4). May stabilize the dimeric form of the enzyme.;
Active site	No current data
Pfam	PF00667 PF00258 PF00175 PF02898
InterPro	IPR003097 IPR017927 IPR001094 IPR008254 IPR001709 IPR029039 IPR039261 IPR023173 IPR012144 IPR004030 IPR036119 IPR001433 IPR017938