Uniprot ID	P30189
Uniprot Name	TOP1_DROME
Taxonomy ID	7227
Sequence	M S G D V A A E N S I H I Q N G G S C E V V Q S N G V T T N G H G H H H H H H S S S S S S S K H K S S S K D K H R D R E R E H K S S N S S S S S K E H K S S S R D K D R H K S S S S S S K H R D K D K E R D G S S N S H R S G S S S S H K D K D G S S S S K H K S S S G H H K R S S K D K E R R D K D K D R G S S S S S R H K S S S S S R D K E R S S S S H K S S S S S S S S K S K H S S S R H S S S S S S K D H P S Y D G V F V K P E P V S Q Q L M H S G S V D A F Q M Q Q L G S Y E A A A A G T N F N G N G N V A G A N Y K N G Y E E S I V D I K K E E E S F N N L S Q A S S C D Y S M S Q F R A D E P P F V V K H E Q S Y A E E D S T M N Y N D H D D D A D E M N D D E E D V P L A M R K R K Q E A T D R P D G G M D N D D D D D I P L L A R K K V K K E K I K K E S K E K S K K R V K E E P S D D Y G N V K P K K K K M K K E P E P A V S P G K R Q K A K A K V E E E E V W R W W E E E K R A D G V K W S T L E H K G P V F A P R Y E R V P R N V R F Y Y D G K P L E L S E E T E E A A T F Y A K M L N H D Y C T K E V F N N N F F K D F R K S M T P R E R E I I K D F R K C N F Q E M F N Y F Q A E S E K R K A A S K E E K L I K K N E N E A L M K E F G F C M I D G H K E K I G N F R L E P P G L F R G R G E H P K M G M I K R R I Q A S D V S I N C G K D S K V P S P P P G S R W K E V R H D N T V T W L A S W I E N V Q G Q V K Y I M L N P S S K L K G E K D H I K Y E T A R R L D K V I D K I R A T Y R D E W K S K E M R V R Q R A V A L Y F I D K L A L R A G N E K D E D Q A D T V G C C S L R V E H V Q L H K E L N G K E N V V V F D F P G K D S I R Y Y N E V E V E K R V F K N L E L F M E H K K E G D D L F D R L N T Q V L N E H L K E L M E G L T A K V F R T Y N A S K T L Q S Q L D L L T D P S A T V P E K L L A Y N R A N R A V A I L C N H Q R S V P K S H E K S M E N L K E K I K A K R E A I E K C E S E Y H S R D E K K G K Q L E R L R D Q L K K L E L Q E T D R D E N K T I A L G T S K L N Y L D P R I S V A W C K K H D V P I E K I F N K T Q R T K F L W A V H M A D E N Y R F
Cofactor	No current data
Active site	ACT_SITE 930 930 O-(3'-phospho-DNA)-tyrosine intermediate. {ECO:0000255|PROSITE-ProRule:PRU10130}.
Pfam	PF14370 PF01028 PF02919
InterPro	IPR011010 IPR013034 IPR013030 IPR001631 IPR018521 IPR025834 IPR014711 IPR014727 IPR013500 IPR008336 IPR036202 IPR013499