Uniprot ID	P35228
Uniprot Name	NOS2_HUMAN
Taxonomy ID	9606
Sequence	M A C P W K F L F K T K F H Q Y A M N G E K D I N N N V E K A P C A T S S P V T Q D D L Q Y H N L S K Q Q N E S P Q P L V E T G K K S P E S L V K L D A T P L S S P R H V R I K N W G S G M T F Q D T L H H K A K G I L T C R S K S C L G S I M T P K S L T R G P R D K P T P P D E L L P Q A I E F V N Q Y Y G S F K E A K I E E H L A R V E A V T K E I E T T G T Y Q L T G D E L I F A T K Q A W R N A P R C I G R I Q W S N L Q V F D A R S C S T A R E M F E H I C R H V R Y S T N N G N I R S A I T V F P Q R S D G K H D F R V W N A Q L I R Y A G Y Q M P D G S I R G D P A N V E F T Q L C I D L G W K P K Y G R F D V V P L V L Q A N G R D P E L F E I P P D L V L E V A M E H P K Y E W F R E L E L K W Y A L P A V A N M L L E V G G L E F P G C P F N G W Y M G T E I G V R D F C D V Q R Y N I L E E V G R R M G L E T H K L A S L W K D Q A V V E I N I A V L H S F Q K Q N V T I M D H H S A A E S F M K Y M Q N E Y R S R G G C P A D W I W L V P P M S G S I T P V F H Q E M L N Y V L S P F Y Y Y Q V E A W K T H V W Q D E K R R P K R R E I P L K V L V K A V L F A C M L M R K T M A S R V R V T I L F A T E T G K S E A L A W D L G A L F S C A F N P K V V C M D K Y R L S C L E E E R L L L V V T S T F G N G D C P G N G E K L K K S L F M L K E L N N K F R Y A V F G L G S S M Y P R F C A F A H D I D Q K L S H L G A S Q L T P M G E G D E L S G Q E D A F R S W A V Q T F K A A C E T F D V R G K Q H I Q I P K L Y T S N V T W D P H H Y R L V Q D S Q P L D L S K A L S S M H A K N V F T M R L K S R Q N L Q S P T S S R A T I L V E L S C E D G Q G L N Y L P G E H L G V C P G N Q P A L V Q G I L E R V V D G P T P H Q T V R L E A L D E S G S Y W V S D K R L P P C S L S Q A L T Y F L D I T T P P T Q L L L Q K L A Q V A T E E P E R Q R L E A L C Q P S E Y S K W K F T N S P T F L E V L E E F P S L R V S A G F L L S Q L P I L K P R F Y S I S S S R D H T P T E I H L T V A V V T Y H T R D G Q G P L H H G V C S T W L N S L K P Q D P V P C F V R N A S G F H L P E D P S H P C I L I G P G T G I A P F R S F W Q Q R L H D S Q H K G V R G G R M T L V F G C R R P D E D H I Y Q E E M L E M A Q K G V L H A V H T A Y S R L P G K P K V Y V Q D I L R Q Q L A S E V L R V L H K E P G H L Y V C G D V R M A R D V A H T L K Q L V A A K L K L N E E Q V E D Y F F Q L K S Q K R Y H E D I F G A V F P Y E A K K D R V A V Q P S S L E M S A L
Cofactor	COFACTOR: Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250}; ; COFACTOR: Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250}; Note=Binds 1 FAD. {ECO:0000250}; COFACTOR: Name=FMN; Xref=ChEBI:CHEBI:58210; Evidence={ECO:0000250}; Note=Binds 1 FMN. {ECO:0000250}; COFACTOR: Name=(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin; Xref=ChEBI:CHEBI:59560; Evidence={ECO:0000250}; Note=Tetrahydrobiopterin (BH4). May stabilize the dimeric form of the enzyme. {ECO:0000250};
Active site	No current data
Pfam	PF00667 PF00258 PF00175 PF02898
InterPro	IPR003097 IPR017927 IPR001094 IPR008254 IPR001709 IPR029039 IPR039261 IPR023173 IPR012144 IPR004030 IPR036119 IPR001433 IPR017938