Uniprot ID	P35355
Uniprot Name	PGH2_RAT
Taxonomy ID	10116
Sequence	M L F R A V L L C A A L A L S H A A N P C C S N P C Q N R G E C M S I G F D Q Y K C D C T R T G F Y G E N C T T P E F L T R I K L L L K P T P N T V H Y I L T H F K G V W N I V N N I P F L R N S I M R Y V L T S R S H L I D S P P T Y N V H Y G Y K S W E A F S N L S Y Y T R A L P P V A D D C P T P M G V K G N K E L P D S K E V L E K V L L R R E F I P D P Q G T N M M F A F F A Q H F T H Q F F K T D Q K R G P G F T R G L G H G V D L N H V Y G E T L D R Q H K L R L F Q D G K L K Y Q V I G G E V Y P P T V K D T Q V D M I Y P P H V P E H L R F A V G Q E V F G L V P G L M M Y A T I W L R E H N R V C D I L K Q E H P E W D D E R L F Q T S R L I L I G E T I K I V I E D Y V Q H L S G Y H F K L K F D P E L L F N Q Q F Q Y Q N R I A S E F N T L Y H W H P L L P D T F N I E D Q E Y T F K Q F L Y N N S I L L E H G L A H F V E S F T R Q I A G R V A G G R N V P I A V Q A V A K A S I D Q S R E M K Y Q S L N E Y R K R F S L K P Y T S F E E L T G E K E M A A E L K A L Y H D I D A M E L Y P A L L V E K P R P D A I F G E T M V E L G A P F S L K G L M G N P I C S P Q Y W K P S T F G G E V G F R I I N T A S I Q S L I C N N V K G C P F A S F N V Q D P Q P T K T A T I N A S A S H S R L D D I N P T V L I K R R S T E L
Cofactor	COFACTOR: Name=heme b; Xref=ChEBI:CHEBI:60344; Evidence={ECO:0000250|UniProtKB:Q05769}; Note=Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit. {ECO:0000250|UniProtKB:Q05769};
Active site	ACT_SITE 193 193 Proton acceptor. {ECO:0000255|PROSITE-ProRule:PRU00298}.; ACT_SITE 371 371 For cyclooxygenase activity. {ECO:0000250|UniProtKB:Q05769}.
Pfam	PF03098 PF00008
InterPro	IPR029576 IPR000742 IPR019791 IPR010255 IPR037120