Uniprot ID	P37177
Uniprot Name	PT1P_ECOLI
Taxonomy ID	83333
Sequence	M L T R L R E I V E K V A S A P R L N E A L N I L V T D I C L A M D T E V C S V Y L A D H D R R C Y Y L M A T R G L K K P R G R T V T L A F D E G I V G L V G R L A E P I N L A D A Q K H P S F K Y I P S V K E E R F R A F L G V P I I Q R R Q L L G V L V V Q Q R E L R Q Y D E S E E S F L V T L A T Q M A A I L S Q S Q L T A L F G Q Y R Q T R I R A L P A A P G V A I A E G W Q D A T L P L M E Q V Y Q A S T L D P A L E R E R L T G A L E E A A N E F R R Y S K R F A A G A Q K E T A A I F D L Y S H L L S D T R L R R E L F A E V D K G S V A E W A V K T V I E K F A E Q F A A L S D N Y L K E R A G D L R A L G Q R L L F H L D D A N Q G P N A W P E R F I L V A D E L S A T T L A E L P Q D R L V G V V V R D G A A N S H A A I M V R A L G I P T V M G A D I Q P S V L H R R T L I V D G Y R G E L L V D P E P V L L Q E Y Q R L I S E E I E L S R L A E D D V N L P A Q L K S G E R I K V M L N A G L S P E H E E K L G S R I D G I G L Y R T E I P F M L Q S G F P S E E E Q V A Q Y Q G M L Q M F N D K P V T L R T L D V G A D K Q L P Y M P I S E E N P C L G W R G I R I T L D Q P E I F L I Q V R A M L R A N A A T G N L N I L L P M V T S L D E V D E A R R L I E R A G R E V E E M I G Y E I P K P R I G I M L E V P S M V F M L P H L A K R V D F I S V G T N D L T Q Y I L A V D R N N T R V A N I Y D S L H P A M L R A L A M I A R E A E I H G I D L R L C G E M A G D P M C V A I L I G L G Y R H L S M N G R S V A R A K Y L L R R I D Y A E A E N L A Q R S L E A Q L A T E V R H Q V A A F M E R R G M G G L I R G G L
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:10473571}; Note=Mn(2+) allows activity only at low concentrations. In the presence of low concentrations of Co(2+) or Ni(2+), activity could be measured, but at concentrations above 0.2 mM, strong inhibition is observed. {ECO:0000269|PubMed:10473571};
Active site	ACT_SITE 356 356 Tele-phosphohistidine intermediate. {ECO:0000250|UniProtKB:P08839}.; ACT_SITE 668 668 Proton donor. {ECO:0000250|UniProtKB:P08839}.
Pfam	PF01590 PF05524 PF00391 PF02896
InterPro	IPR003018 IPR029016 IPR008279 IPR018274 IPR000121 IPR023151 IPR036637 IPR006318 IPR008731 IPR036618 IPR015813 IPR040442