Uniprot ID	P43704
Uniprot Name	TOP3_HAEIN
Taxonomy ID	71421
Sequence	M R L F I A E K P S L A R A I A D V L P K P H Q R G D G F I K C G D N D V V T W C V G H L L E Q A E P D A Y D P K F K Q W R L E H L P I I P E K W Q L L P R K E V K K Q L S V V E K L I H Q A D T L V N A G D P D R E G Q L L V D E V F S Y A N L S A E K R D K I L R C L I S D L N P S A V E K A V K K L Q P N R N F I P L A T S A L A R A R A D W L Y G I N M T R A Y T I R G R Q T G Y D G V L S V G R V Q T P V L G L I V R R D L E I E H F Q P K D F F E V Q A W V N P E S K E E K T P E K S T A L F S A L W Q P S K A C E D Y Q D D D G R V L S K G L A E K V V K R I T N Q P A E V T E Y K D V R E K E T A P L P Y S L S A L Q I D A A K R F G M S A Q A V L D T C Q R L Y E T H R L I T Y P R S D C R Y L P E E H F A E R H N V L N A I S T H C E A Y Q V L P N V I L T E Q R N R C W N D K K V E A H H A I I P T A K N R P V N L T Q E E R N I Y S L I A R Q Y L M Q F C P D A E Y R K S K I T L N I A G G T F I A Q A R N L Q T A G W K E L L G K E D D T E N Q E P L L P I V K K G Q I L H C E R G E V M S K K T Q P P K P F T D A T L L S A M T G I A R F V Q D K E L K K I L R E T D G L G T E A T R A G I I E L L F K R G F L T K K G R N I H S T E T G R I L I Q A L P N I A T Q P D M T A H W E S Q L T D I S Q K Q A T Y Q Q F M H N L N Q I L P D L V R F V D L N A L R Q L S R I K M I K S D R A K P K S A V K K S S K S N G E T D
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000255|HAMAP-Rule:MF_00953}; Note=Binds two Mg(2+) per subunit. {ECO:0000255|HAMAP-Rule:MF_00953};
Active site	ACT_SITE 337 337 O-(5'-phospho-DNA)-tyrosine intermediate. {ECO:0000255|HAMAP-Rule:MF_00953}.
Pfam	PF01131 PF01751
InterPro	IPR000380 IPR003601 IPR023406 IPR013497 IPR013824 IPR013825 IPR013826 IPR023405 IPR003602 IPR005738 IPR006171 IPR034144