Uniprot ID	P47368
Uniprot Name	TOP1_MYCGE
Taxonomy ID	243273
Sequence	M I K N L V V I E S P N K V K T L K Q Y L P S D E F E I V S T V G H I R E M V Y K N F G F D E N T Y T P I W E D W T K N K Q K N P K Q K H L L S K F E I I K S I K A K A S D A Q N I F L A S D P D R E G E A I S W H V Y D L L D Q K D K A K C K R I T F N E I T K K A V V D A L K Q P R N I D L N W V E S Q F A R Q I L D R M I G F R L S R L L N S Y L Q A K S A G R V Q S V A L R F L E E R E K E I A K F V P R F W W T V D V L L N K E N N Q K V V C A N K S I P L V L R E I N P E L S A S L K L D F E A A E N V S G I D F L N E A S A T R F A N Q L T G E Y E V Y F I D E P K I Y Y S S P N P V Y T T A S L Q K D A I N K L G W S S K K V T M V A Q R L Y E G I S V N G K Q T A L I S Y P R T D S I R I S N Q F Q S E C E K Y I E K E F G S H Y L A D K N K L K R H K K D E K I I Q D A H E G I H P T Y I T I T P N D L K N G V K R D E F L L Y R L I W I R T V A S L M A D A K T S R T I V R F I N Q K N K F Y T S S K S L L F D G Y Q R L Y E E I K P N T K D E L Y I D L S K L K I G D K F S F E K I S V N E H K T N P P P R Y T Q A S L I E E L E K S N I G R P S T Y N T M A S V N L E R G Y A N L V N R F F Y I T E L G E K V N N E L S K H F G N V I N K E F T K K M E K S L D E I A E N K V N Y Q E F L K Q F W T N F K S D V K L A E N S I Q K V K K E K E L V E R D C P K C N Q P L V Y R Y T K R G N E K F V G C S D F P K C K Y S E F S N P K P K L T L E T L D E L C P E C N N K L V K R R T K F N A K K T F I G C S N F P N C R F I K K D N A A E F K Q
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000255|HAMAP-Rule:MF_00952}; Note=Binds two Mg(2+) per subunit. {ECO:0000255|HAMAP-Rule:MF_00952};
Active site	ACT_SITE 334 334 O-(5'-phospho-DNA)-tyrosine intermediate. {ECO:0000255|HAMAP-Rule:MF_00952}.
Pfam	PF01131 PF01751 PF01396
InterPro	IPR000380 IPR003601 IPR023406 IPR013497 IPR013824 IPR013825 IPR013826 IPR023405 IPR003602 IPR013498 IPR005733 IPR028612 IPR006171