Uniprot ID	P47989
Uniprot Name	XDH_HUMAN
Taxonomy ID	9606
Sequence	M T A D K L V F F V N G R K V V E K N A D P E T T L L A Y L R R K L G L S G T K L G C G E G G C G A C T V M L S K Y D R L Q N K I V H F S A N A C L A P I C S L H H V A V T T V E G I G S T K T R L H P V Q E R I A K S H G S Q C G F C T P G I V M S M Y T L L R N Q P E P T M E E I E N A F Q G N L C R C T G Y R P I L Q G F R T F A R D G G C C G G D G N N P N C C M N Q K K D H S V S L S P S L F K P E E F T P L D P T Q E P I F P P E L L R L K D T P R K Q L R F E G E R V T W I Q A S T L K E L L D L K A Q H P D A K L V V G N T E I G I E M K F K N M L F P M I V C P A W I P E L N S V E H G P D G I S F G A A C P L S I V E K T L V D A V A K L P A Q K T E V F R G V L E Q L R W F A G K Q V K S V A S V G G N I I T A S P I S D L N P V F M A S G A K L T L V S R G T R R T V Q M D H T F F P G Y R K T L L S P E E I L L S I E I P Y S R E G E Y F S A F K Q A S R R E D D I A K V T S G M R V L F K P G T T E V Q E L A L C Y G G M A N R T I S A L K T T Q R Q L S K L W K E E L L Q D V C A G L A E E L H L P P D A P G G M V D F R C T L T L S F F F K F Y L T V L Q K L G Q E N L E D K C G K L D P T F A S A T L L F Q K D P P A D V Q L F Q E V P K G Q S E E D M V G R P L P H L A A D M Q A S G E A V Y C D D I P R Y E N E L S L R L V T S T R A H A K I K S I D T S E A K K V P G F V C F I S A D D V P G S N I T G I C N D E T V F A K D K V T C V G H I I G A V V A D T P E H T Q R A A Q G V K I T Y E E L P A I I T I E D A I K N N S F Y G P E L K I E K G D L K K G F S E A D N V V S G E I Y I G G Q E H F Y L E T H C T I A V P K G E A G E M E L F V S T Q N T M K T Q S F V A K M L G V P A N R I V V R V K R M G G G F G G K E T R S T V V S T A V A L A A Y K T G R P V R C M L D R D E D M L I T G G R H P F L A R Y K V G F M K T G T V V A L E V D H F S N V G N T Q D L S Q S I M E R A L F H M D N C Y K I P N I R G T G R L C K T N L P S N T A F R G F G G P Q G M L I A E C W M S E V A V T C G M P A E E V R R K N L Y K E G D L T H F N Q K L E G F T L P R C W E E C L A S S Q Y H A R K S E V D K F N K E N C W K K R G L C I I P T K F G I S F T V P F L N Q A G A L L H V Y T D G S V L L T H G G T E M G Q G L H T K M V Q V A S R A L K I P T S K I Y I S E T S T N T V P N T S P T A A S V S A D L N G Q A V Y A A C Q T I L K R L E P Y K K K N P S G S W E D W V T A A Y M D T V S L S A T G F Y R T P N L G Y S F E T N S G N P F H Y F S Y G V A C S E V E I D C L T G D H K N L R T D I V M D V G S S L N P A I D I G Q V E G A F V Q G L G L F T L E E L H Y S P E G S L H T R G P S T Y K I P A F G S I P I E F R V S L L R D C P N K K A I Y A S K A V G E P P L F L A A S I F F A I K D A I R A A R A Q H T G N N V K E L F R L D S P A T P E K I R N A C V D K F T T L C V T G V P E N C K P W S V R V
Cofactor	COFACTOR: Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:49601; Evidence={ECO:0000269|PubMed:17301077}; Note=Binds 2 [2Fe-2S] clusters. {ECO:0000269|PubMed:17301077}; COFACTOR: Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000269|PubMed:17301077}; ; COFACTOR: Name=Mo-molybdopterin; Xref=ChEBI:CHEBI:71302; Evidence={ECO:0000269|PubMed:17301077}; Note=Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit. {ECO:0000269|PubMed:17301077};
Active site	ACT_SITE 1262 1262 Proton acceptor.
Pfam	PF01315 PF02738 PF03450 PF00941 PF00111 PF01799
InterPro	IPR002888 IPR036884 IPR036010 IPR001041 IPR006058 IPR000674 IPR036856 IPR016208 IPR008274 IPR037165 IPR005107 IPR036683 IPR016166 IPR036318 IPR002346 IPR022407 IPR014307