Uniprot ID	P49327
Uniprot Name	FAS_HUMAN
Taxonomy ID	9606
Sequence	M E E V V I A G M S G K L P E S E N L Q E F W D N L I G G V D M V T D D D R R W K A G L Y G L P R R S G K L K D L S R F D A S F F G V H P K Q A H T M D P Q L R L L L E V T Y E A I V D G G I N P D S L R G T H T G V W V G V S G S E T S E A L S R D P E T L V G Y S M V G C Q R A M M A N R L S F F F D F R G P S I A L D T A C S S S L M A L Q N A Y Q A I H S G Q C P A A I V G G I N V L L K P N T S V Q F L R L G M L S P E G T C K A F D T A G N G Y C R S E G V V A V L L T K K S L A R R V Y A T I L N A G T N T D G F K E Q G V T F P S G D I Q E Q L I R S L Y Q S A G V A P E S F E Y I E A H G T G T K V G D P Q E L N G I T R A L C A T R Q E P L L I G S T K S N M G H P E P A S G L A A L A K V L L S L E H G L W A P N L H F H S P N P E I P A L L D G R L Q V V D Q P L P V R G G N V G I N S F G F G G S N V H I I L R P N T Q P P P A P A P H A T L P R L L R A S G R T P E A V Q K L L E Q G L R H S Q D L A F L S M L N D I A A V P A T A M P F R G Y A V L G G E R G G P E V Q Q V P A G E R P L W F I C S G M G T Q W R G M G L S L M R L D R F R D S I L R S D E A V K P F G L K V S Q L L L S T D E S T F D D I V H S F V S L T A I Q I G L I D L L S C M G L R P D G I V G H S L G E V A C G Y A D G C L S Q E E A V L A A Y W R G Q C I K E A H L P P G A M A A V G L S W E E C K Q R C P P G V V P A C H N S K D T V T I S G P Q A P V F E F V E Q L R K E G V F A K E V R T G G M A F H S Y F M E A I A P P L L Q E L K K V I R E P K P R S A R W L S T S I P E A Q W H S S L A R T S S A E Y N V N N L V S P V L F Q E A L W H V P E H A V V L E I A P H A L L Q A V L K R G L K P S C T I I P L M K K D H R D N L E F F L A G I G R L H L S G I D A N P N A L F P P V E F P A P R G T P L I S P L I K W D H S L A W D V P A A E D F P N G S G S P S A A I Y N I D T S S E S P D H Y L V D H T L D G R V L F P A T G Y L S I V W K T L A R A L G L G V E Q L P V V F E D V V L H Q A T I L P K T G T V S L E V R L L E A S R A F E V S E N G N L V V S G K V Y Q W D D P D P R L F D H P E S P T P N P T E P L F L A Q A E V Y K E L R L R G Y D Y G P H F Q G I L E A S L E G D S G R L L W K D N W V S F M D T M L Q M S I L G S A K H G L Y L P T R V T A I H I D P A T H R Q K L Y T L Q D K A Q V A D V V V S R W L R V T V A G G V H I S G L H T E S A P R R Q Q E Q Q V P I L E K F C F T P H T E E G C L S E R A A L Q E E L Q L C K G L V Q A L Q T K V T Q Q G L K M V V P G L D G A Q I P R D P S Q Q E L P R L L S A A C R L Q L N G N L Q L E L A Q V L A Q E R P K L P E D P L L S G L L D S P A L K A C L D T A V E N M P S L K M K V V E V L A G H G H L Y S R I P G L L S P H P L L Q L S Y T A T D R H P Q A L E A A Q A E L Q Q H D V A Q G Q W D P A D P A P S A L G S A D L L V C N C A V A A L G D P A S A L S N M V A A L R E G G F L L L H T L L R G H P L G D I V A F L T S T E P Q Y G Q G I L S Q D A W E S L F S R V S L R L V G L K K S F Y G S T L F L C R R P T P Q D S P I F L P V D D T S F R W V E S L K G I L A D E D S S R P V W L K A I N C A T S G V V G L V N C L R R E P G G N R L R C V L L S N L S S T S H V P E V D P G S A E L Q K V L Q G D L V M N V Y R D G A W G A F R H F L L E E D K P E E P T A H A F V S T L T R G D L S S I R W V C S S L R H A Q P T C P G A Q L C T V Y Y A S L N F R D I M L A T G K L S P D A I P G K W T S Q D S L L G M E F S G R D A S G K R V M G L V P A K G L A T S V L L S P D F L W D V P S N W T L E E A A S V P V V Y S T A Y Y A L V V R G R V R P G E T L L I H S G S G G V G Q A A I A I A L S L G C R V F T T V G S A E K R A Y L Q A R F P Q L D S T S F A N S R D T S F E Q H V L W H T G G K G V D L V L N S L A E E K L Q A S V R C L A T H G R F L E I G K F D L S Q N H P L G M A I F L K N V T F H G V L L D A F F N E S S A D W R E V W A L V Q A G I R D G V V R P L K C T V F H G A Q V E D A F R Y M A Q G K H I G K V V V Q V L A E E P E A V L K G A K P K L M S A I S K T F C P A H K S Y I I A G G L G G F G L E L A Q W L I Q R G V Q K L V L T S R S G I R T G Y Q A K Q V R R W R R Q G V Q V Q V S T S N I S S L E G A R G L I A E A A Q L G P V G G V F N L A V V L R D G L L E N Q T P E F F Q D V C K P K Y S G T L N L D R V T R E A C P E L D Y F V V F S S V S C G R G N A G Q S N Y G F A N S A M E R I C E K R R H E G L P G L A V Q W G A I G D V G I L V E T M S T N D T I V S G T L P Q R M A S C L E V L D L F L N Q P H M V L S S F V L A E K A A A Y R D R D S Q R D L V E A V A H I L G I R D L A A V N L D S S L A D L G L D S L M S V E V R Q T L E R E L N L V L S V R E V R Q L T L R K L Q E L S S K A D E A S E L A C P T P K E D G L A Q Q Q T Q L N L R S L L V N P E G P T L M R L N S V Q S S E R P L F L V H P I E G S T T V F H S L A S R L S I P T Y G L Q C T R A A P L D S I H S L A A Y Y I D C I R Q V Q P E G P Y R V A G Y S Y G A C V A F E M C S Q L Q A Q Q S P A P T H N S L F L F D G S P T Y V L A Y T Q S Y R A K L T P G C E A E A E T E A I C F F V Q Q F T D M E H N R V L E A L L P L K G L E E R V A A A V D L I I K S H Q G L D R Q E L S F A A R S F Y Y K L R A A E Q Y T P K A K Y H G N V M L L R A K T G G A Y G E D L G A D Y N L S Q V C D G K V S V H V I E G D H R T L L E G S G L E S I I S I I H S S L A E P R V S V R E G
Cofactor	No current data
Active site	ACT_SITE 161 161 For beta-ketoacyl synthase activity. {ECO:0000255|PROSITE-ProRule:PRU10022}.; ACT_SITE 581 581 For malonyltransferase activity. {ECO:0000255|PROSITE-ProRule:PRU10022}.; ACT_SITE 878 878 For beta-hydroxyacyl dehydratase activity. {ECO:0000255|PROSITE-ProRule:PRU10022}.; ACT_SITE 2308 2308 For thioesterase activity. {ECO:0000255|PROSITE-ProRule:PRU10022, ECO:0000269|PubMed:17618296}.; ACT_SITE 2481 2481 For thioesterase activity. {ECO:0000255|PROSITE-ProRule:PRU10022}.
Pfam	PF00698 PF00107 PF16197 PF00109 PF02801 PF08659 PF08242 PF00550 PF14765 PF00975
InterPro	IPR029058 IPR001227 IPR036736 IPR014043 IPR016035 IPR013149 IPR023102 IPR011032 IPR032821 IPR018201 IPR014031 IPR014030 IPR016036 IPR013217 IPR036291 IPR020801 IPR020841 IPR020807 IPR042104 IPR020843 IPR013968 IPR020806 IPR009081 IPR006162 IPR029063 IPR001031 IPR016039