Uniprot ID	P50299
Uniprot Name	METK1_HORVU
Taxonomy ID	4513
Sequence	M A A E T F L F T S E S V N E G H P D K L C D Q V S D A V L D A C L A Q D P D S K V A C E T C T K T N M V M V F G E I T T K A T V D Y E K I V R D T C R D I G F I S D D V G L D A D H C K V L V N I E Q Q S P D I A Q G V H G H F T K R P E E V G A G D Q G I M F G Y A T D E T P E L M P L T H M L A T K L G A R L T E V R K N G T C A W L R P D G K T Q V T I E Y L N E G G A M V P V R V H T V L I S T Q H D E T V T N D E I A A D L K E H V I K P V I P G K Y L D E N T I F H L N P S G R F V I G G P H G D A G L T A R K I I I D T Y G G W G A H G G G A F S G K D P T K V D R S G A Y I A R Q A A K S I I A S G L A R R C I V Q I S Y A I G V P E P L S V F V D S Y G T G K I P D R E I L K L V K E N F D F R P G M I T I N L D L K K G G N R F I K T A A Y G H F G R D D A D F T W E V V K P L K F D K A S A
Cofactor	COFACTOR: Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250|UniProtKB:Q96551}; Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250|UniProtKB:Q96551}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000250|UniProtKB:Q96551}; Note=Binds 2 divalent ions per subunit. The metal ions interact primarily with the substrate (By similarity). Can utilize magnesium, manganese or cobalt (in vitro) (By similarity). {ECO:0000250|UniProtKB:P13444, ECO:0000250|UniProtKB:Q96551}; COFACTOR: Name=K(+); Xref=ChEBI:CHEBI:29103; Evidence={ECO:0000250|UniProtKB:Q96551}; Note=Binds 1 potassium ion per subunit. The potassium ion interacts primarily with the substrate (By similarity). {ECO:0000250|UniProtKB:P13444};
Active site	No current data
Pfam	PF02773 PF02772 PF00438
InterPro	IPR022631 IPR022630 IPR022629 IPR022628 IPR002133 IPR022636