Uniprot ID	P51178
Uniprot Name	PLCD1_HUMAN
Taxonomy ID	9606
Sequence	M D S G R D F L T L H G L Q D D E D L Q A L L K G S Q L L K V K S S S W R R E R F Y K L Q E D C K T I W Q E S R K V M R T P E S Q L F S I E D I Q E V R M G H R T E G L E K F A R D V P E D R C F S I V F K D Q R N T L D L I A P S P A D A Q H W V L G L H K I I H H S G S M D Q R Q K L Q H W I H S C L R K A D K N K D N K M S F K E L Q N F L K E L N I Q V D D S Y A R K I F R E C D H S Q T D S L E D E E I E A F Y K M L T Q R V E I D R T F A E A A G S G E T L S V D Q L V T F L Q H Q Q R E E A A G P A L A L S L I E R Y E P S E T A K A Q R Q M T K D G F L M Y L L S A D G S A F S L A H R R V Y Q D M G Q P L S H Y L V S S S H N T Y L L E D Q L A G P S S T E A Y I R A L C K G C R C L E L D C W D G P N Q E P I I Y H G Y T F T S K I L F C D V L R A I R D Y A F K A S P Y P V I L S L E N H C T L E Q Q R V M A R H L H A I L G P M L L N R P L D G V T N S L P S P E Q L K G K I L L K G K K L G G L L P P G G E G G P E A T V V S D E D E A A E M E D E A V R S R V Q H K P K E D K L R L A Q E L S D M V I Y C K S V H F G G F S S P G T P G Q A F Y E M A S F S E N R A L R L L Q E S G N G F V R H N V G H L S R I Y P A G W R T D S S N Y S P V E M W N G G C Q I V A L N F Q T P G P E M D V Y Q G R F Q D N G A C G Y V L K P A F L R D P N G T F N P R A L A Q G P W W A R K R L N I R V I S G Q Q L P K V N K N K N S I V D P K V T V E I H G V S R D V A S R Q T A V I T N N G F N P W W D T E F A F E V V V P D L A L I R F L V E D Y D A S S K N D F I G Q S T I P L N S L K Q G Y R H V H L M S K N G D Q H P S A T L F V K I S L Q D
Cofactor	COFACTOR: Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Note=Binds 3 Ca(2+) ions per subunit. Two of the Ca(2+) ions are bound to the C2 domain. {ECO:0000250};
Active site	ACT_SITE 311 311 {ECO:0000255|PROSITE-ProRule:PRU00270}.; ACT_SITE 356 356 {ECO:0000255|PROSITE-ProRule:PRU00270}.
Pfam	PF00168 PF09279 PF00388 PF00387
InterPro	IPR000008 IPR035892 IPR011992 IPR018247 IPR002048 IPR011993 IPR001849 IPR001192 IPR028391 IPR017946 IPR015359 IPR000909 IPR001711