Uniprot ID	P54748
Uniprot Name	PDE4A_RAT
Taxonomy ID	10116
Sequence	M E P P A A P S E R S L S L S L P G P R E G Q A T L K P P P Q H L W R Q P R T P I R I Q Q R G Y P D S A E R S E T E R S P H R P I E R A D A V D T G D R P G L R T T R M S W P S S F H G T G T G G G S S R R L E A E N G P T P S P G R S P L D S Q A S P G L V L H A G A T T S Q R R E S F L Y R S D S D Y D M S P K A V S R S S S V A S E A H A E D L I V T P F A Q V L A S L R S V R S N F S L L T N V P I P S N K R S P L G G P P S V C K A T L S E E T C Q Q L A R E T L E E L D W C L E Q L E T M Q T Y R S V S E M A S H K F K R M L N R E L T H L S E M S R S G N Q V S E Y I S N T F L D K Q N E V E I P S P T P R Q R A F Q Q P P P S V L R Q S Q P M S Q I T G L K K L V H T G S L N T N V P R F G V K T D Q E D L L A Q E L E N L S K W G L N I F C V S E Y A G G R S L S C I M Y T I F Q E R D L L K K F H I P V D T M M M Y M L T L E D H Y H A D V A Y H N S L H A A D V L Q S T H V L L A T P A L D A V F T D L E I L A A L F A A A I H D V D H P G V S N Q F L I N T N S E L A L M Y N D E S V L E N H H L A V G F K L L Q E E N C D I F Q N L S K R Q R Q S L R K M V I D M V L A T D M S K H M T L L A D L K T M V E T K K V T S S G V L L L D N Y S D R I Q V L R N M V H C A D L S N P T K P L E L Y R Q W T D R I M A E F F Q Q G D R E R E R G M E I S P M C D K H T A S V E K S Q V G F I D Y I V H P L W E T W A D L V H P D A Q D I L D T L E D N R D W Y H S A I R Q S P S P P L E E E P G G L G H P S L P D K F Q F E L T L E E E E E E D S L E V P G L P T T E E T F L A A E D A R A Q A V D W S K V K G P S T T V V E V A E R L K Q E T A S A Y G A P Q E S M E A V G C S F S P G T P I L P D V R T L S S S E E A P G L L G L P S T A A E V E A P R D H L A A T R A C S A C S G T S G D N S A I I S A P G R W G S G G D P A
Cofactor	COFACTOR: Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; Evidence={ECO:0000250}; Note=Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. {ECO:0000250};
Active site	ACT_SITE 419 419 Proton donor. {ECO:0000250}.
Pfam	PF18100 PF00233
InterPro	IPR003607 IPR040844 IPR023088 IPR002073 IPR036971 IPR023174