Uniprot ID	P56900
Uniprot Name	TKT_SINMW
Taxonomy ID	366394
Sequence	M N V S Q Q I E P R A A A S E R N M A D A I R F L S M D A V E K A N S G H P G M P M G M A D A V T V L F N R F I R I D P S L P D W P D R D R F V L S A G H G S M L L Y S L H H L I G F A D M P M A E L S S F R Q L G S K T A G H P E Y G H A L G I E T T T G P L G Q G I S T A V G M A M A E Q M M A S R F G S A L C N H F T Y V V A G D G C L Q E G I S H E A I D L A G H L K L R K L V V L W D D N R I S I D G S T D L S T S M N Q L A R F R A A S W D A Q A V D G H D P E A V A K A L E R A R R T R K P S L I A C R T R I G K G A A S M E G S H K T H G A A L G D K E I A A T R E K L G W P H P P F F V P P E I R A A W A K V A A R G R T A R E A W D I R L D A S R S K K R Y E Q T I R R Q F D G E L G D L L A K F R S A H R T R A T K V A T R Q A S Q M A L E V I N G A T A L T I G G S A D L T G S N L T M T S Q T Q P I S P G N F K G R Y L H Y G I R E H G M A A A M N G I A L H G G F I P Y G G T F L V F S D Y A R G A M R L S A L M G L P V I Y V L T H D S I G L G E D G P T H Q P V E H L A M L R A T P N L N V F R P A D I I E T A E C W E I A L G E K N T P S V L A L S R Q A L P M L R R T E G N E N Q S A L G A Y V L R E A R G N R D I T I L A T G S E V E I A V A A A E R L Q A E E G I A A A V V S M P C W E K F E V Q D L A Y R R K V L G D A P R I A I E A A G R L G W D R W M G P D G A F V G M T G F G A S A P A G D L Y R H F G I T A D H V V A E A L E L L R R A Y S E T L P I G A R I G P H P S A H T V R S S Q E A
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000250}; Note=Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+). {ECO:0000250}; COFACTOR: Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937; Evidence={ECO:0000250}; Note=Binds 1 thiamine pyrophosphate per subunit. {ECO:0000250};
Active site	ACT_SITE 415 415 Proton donor. {ECO:0000250}.
Pfam	PF02779 PF02780 PF00456
InterPro	IPR029061 IPR009014 IPR005475 IPR005478 IPR020826 IPR033248 IPR033247 IPR005474