Uniprot ID	P62623
Uniprot Name	ISPH_ECOLI
Taxonomy ID	83333
Sequence	M Q I L L A N P R G F C A G V D R A I S I V E N A L A I Y G A P I Y V R H E V V H N R Y V V D S L R E R G A I F I E Q I S E V P D G A I L I F S A H G V S Q A V R N E A K S R D L T V F D A T C P L V T K V H M E V A R A S R R G E E S I L I G H A G H P E V E G T M G Q Y S N P E G G M Y L V E S P D D V W K L T V K N E E K L S F M T Q T T L S V D D T S D V I D A L R K R F P K I V G P R K D D I C Y A T T N R Q E A V R A L A E Q A E V V L V V G S K N S S N S N R L A E L A Q R M G K R A F L I D D A K D I Q E E W V K E V K C V G V T A G A S A P D I L V Q N V V A R L Q Q L G G G E A I P L E G R E E N I V F E V P K E L R V D I R E V D
Cofactor	COFACTOR: Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence={ECO:0000269|PubMed:12706830, ECO:0000269|PubMed:20080550, ECO:0000269|PubMed:22012762, ECO:0000269|PubMed:22137895, ECO:0000269|PubMed:22687151}; Note=Was shown to bind 1 [3Fe-4S] cluster per subunit (PubMed:19569147, PubMed:20080550, PubMed:15469281). However, it initially contains a [4Fe-4S] cluster which easily degrades into a [3Fe-4S] form in the presence of oxygen (PubMed:12706830, PubMed:22137895, PubMed:20080550, PubMed:22687151). {ECO:0000269|PubMed:12706830, ECO:0000269|PubMed:15469281, ECO:0000269|PubMed:19569147, ECO:0000269|PubMed:20080550, ECO:0000269|PubMed:22137895, ECO:0000269|PubMed:22687151};
Active site	ACT_SITE 126 126 Proton donor. {ECO:0000305|PubMed:22137895, ECO:0000305|PubMed:22687151}.
Pfam	PF02401
InterPro	IPR003451