Uniprot ID	P77585
Uniprot Name	YPDE_ECOLI
Taxonomy ID	83333
Sequence	M D L S L L K A L S E A D A I A S S E Q E V R Q I L L E E A D R L Q K E V R F D G L G S V L I R L N E S T G P K V M I C A H M D E V G F M V R S I S R E G A I D V L P V G N V R M A A R Q L Q P V R I T T R E E C K I P G L L D G D R Q G N D V S A M R V D I G A R S Y D E V M Q A G I R P G D R V T F D T T F Q V L P H Q R V M G K A F D D R L G C Y L L V T L L R E L H D A E L P A E V W L V A S S S E E V G L R G G Q T A T R A V S P D V A I V L D T A C W A K N F D Y G A A N H R Q I G N G P M L V L S D K S L I A P P K L T A W V E T V A A E I G V P L Q A D M F S N G G T D G G A V H L T G T G V P T V V M G P A T R H G H C A A S I A D C R D I L Q M Q Q L L S A L I Q R L T R E T V V Q L T D F R
Cofactor	COFACTOR: Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000269|PubMed:15901689, ECO:0000305}; Name=Ni(2+); Xref=ChEBI:CHEBI:49786; Evidence={ECO:0000269|PubMed:15901689, ECO:0000305}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000269|PubMed:15901689, ECO:0000305}; Name=Cu(2+); Xref=ChEBI:CHEBI:29036; Evidence={ECO:0000269|PubMed:15901689, ECO:0000305}; Note=Binds 2 divalent metal cations per subunit. Can use cobalt, and to a lesser extent, nickel, manganese or copper. {ECO:0000269|PubMed:15901689, ECO:0000305};
Active site	ACT_SITE 198 198 Proton acceptor. {ECO:0000250}.
Pfam	PF05343
InterPro	IPR008007 IPR023367