Uniprot ID	P77625
Uniprot Name	HXPA_ECOLI
Taxonomy ID	83333
Sequence	M R C K G F L F D L D G T L V D S L P A V E R A W S N W A R R H G L A P E E V L A F I H G K Q A I T S L R H F M A G K S E A D I A A E F T R L E H I E A T E T E G I T A L P G A I A L L S H L N K A G I P W A I V T S G S M P V A R A R H K I A G L P A P E V F V T A E R V K R G K P E P D A Y L L G A Q L L G L A P Q E C V V V E D A P A G V L S G L A A G C H V I A V N A P A D T P R L N E V D L V L H S L E Q I T V T K Q P N G D V I I Q
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:16990279}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000269|PubMed:16990279}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000269|PubMed:16990279}; Note=Requires the presence of a divalent metal cation for activity. Can use magnesium, manganese or cobalt. {ECO:0000269|PubMed:16990279};
Active site	ACT_SITE 9 9 Nucleophile. {ECO:0000250|UniProtKB:Q8CHP8}.; ACT_SITE 11 11 Proton donor. {ECO:0000250|UniProtKB:Q8CHP8}.
Pfam	PF13419
InterPro	IPR036412 IPR006439 IPR041492 IPR023214 IPR023198