Uniprot ID	P78325
Uniprot Name	ADAM8_HUMAN
Taxonomy ID	9606
Sequence	M R G L G L W L L G A M M L P A I A P S R P W A L M E Q Y E V V L P W R L P G P R V R R A L P S H L G L H P E R V S Y V L G A T G H N F T L H L R K N R D L L G S G Y T E T Y T A A N G S E V T E Q P R G Q D H C F Y Q G H V E G Y P D S A A S L S T C A G L R G F F Q V G S D L H L I E P L D E G G E G G R H A V Y Q A E H L L Q T A G T C G V S D D S L G S L L G P R T A A V F R P R P G D S L P S R E T R Y V E L Y V V V D N A E F Q M L G S E A A V R H R V L E V V N H V D K L Y Q K L N F R V V L V G L E I W N S Q D R F H V S P D P S V T L E N L L T W Q A R Q R T R R H L H D N V Q L I T G V D F T G T T V G F A R V S A M C S H S S G A V N Q D H S K N P V G V A C T M A H E M G H N L G M D H D E N V Q G C R C Q E R F E A G R C I M A G S I G S S F P R M F S D C S Q A Y L E S F L E R P Q S V C L A N A P D L S H L V G G P V C G N L F V E R G E Q C D C G P P E D C R N R C C N S T T C Q L A E G A Q C A H G T C C Q E C K V K P A G E L C R P K K D M C D L E E F C D G R H P E C P E D A F Q E N G T P C S G G Y C Y N G A C P T L A Q Q C Q A F W G P G G Q A A E E S C F S Y D I L P G C K A S R Y R A D M C G V L Q C K G G Q Q P L G R A I C I V D V C H A L T T E D G T A Y E P V P E G T R C G P E K V C W K G R C Q D L H V Y R S S N C S A Q C H N H G V C N H K Q E C H C H A G W A P P H C A K L L T E V H A A S G S L P V F V V V V L V L L A V V L V T L A G I I V Y R K A R S R I L S R N V A P K T T M G R S N P L F H Q A A S R V P A K G G A P A P S R G P Q E L V P T T H P G Q P A R H P A S S V A L K R P P P A P P V T V S S P P F P V P V Y T R Q A P K Q V I K P T F A P P V P P V K P G A G A A N P G P A E G A V G P K V A L K P P I Q R K Q G A G A P T A P
Cofactor	COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000269|PubMed:22684055}; Note=Binds 1 zinc ion per subunit. {ECO:0000269|PubMed:22684055};
Active site	ACT_SITE 335 335 {ECO:0000255|PROSITE-ProRule:PRU00276, ECO:0000255|PROSITE-ProRule:PRU10095}.
Pfam	PF08516 PF00200 PF01562 PF01421
InterPro	IPR006586 IPR018358 IPR001762 IPR036436 IPR013032 IPR000742 IPR024079 IPR001590 IPR002870 IPR034027