Uniprot ID	P78549
Uniprot Name	NTH_HUMAN
Taxonomy ID	9606
Sequence	M C S P Q E S G M T A L S A R M L T R S R S L G P G A G P R G C R E E P G P L R R R E A A A E A R K S H S P V K R P R K A Q R L R V A Y E G S D S E K G E G A E P L K V P V W E P Q D W Q Q Q L V N I R A M R N K K D A P V D H L G T E H C Y D S S A P P K V R R Y Q V L L S L M L S S Q T K D Q V T A G A M Q R L R A R G L T V D S I L Q T D D A T L G K L I Y P V G F W R S K V K Y I K Q T S A I L Q Q H Y G G D I P A S V A E L V A L P G V G P K M A H L A M A V A W G T V S G I A V D T H V H R I A N R L R W T K K A T K S P E E T R A A L E E W L P R E L W H E I N G L L V G F G Q Q T C L P V H P R C H A C L N Q A L C P A A Q G L
Cofactor	COFACTOR: Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883; Evidence={ECO:0000255|HAMAP-Rule:MF_03183}; Note=Binds 1 [4Fe-4S] cluster. The cluster does not appear to play a role in catalysis, but is probably involved in the proper positioning of the enzyme along the DNA strand. {ECO:0000255|HAMAP-Rule:MF_03183};
Active site	ACT_SITE 220 220 Nucleophile; for N-glycosylase activity. {ECO:0000255|HAMAP-Rule:MF_03183, ECO:0000269|PubMed:9705289}.
Pfam	PF00633 PF00730
InterPro	IPR011257 IPR004036 IPR003651 IPR003265 IPR000445 IPR023170 IPR030841