Uniprot ID	P9WG45
Uniprot Name	GYRB_MYCTU
Taxonomy ID	83332
Sequence	M A A Q K K K A Q D E Y G A A S I T I L E G L E A V R K R P G M Y I G S T G E R G L H H L I W E V V D N A V D E A M A G Y A T T V N V V L L E D G G V E V A D D G R G I P V A T H A S G I P T V D V V M T Q L H A G G K F D S D A Y A I S G G L H G V G V S V V N A L S T R L E V E I K R D G Y E W S Q V Y E K S E P L G L K Q G A P T K K T G S T V R F W A D P A V F E T T E Y D F E T V A R R L Q E M A F L N K G L T I N L T D E R V T Q D E V V D E V V S D V A E A P K S A S E R A A E S T A P H K V K S R T F H Y P G G L V D F V K H I N R T K N A I H S S I V D F S G K G T G H E V E I A M Q W N A G Y S E S V H T F A N T I N T H E G G T H E E G F R S A L T S V V N K Y A K D R K L L K D K D P N L T G D D I R E G L A A V I S V K V S E P Q F E G Q T K T K L G N T E V K S F V Q K V C N E Q L T H W F E A N P T D A K V V V N K A V S S A Q A R I A A R K A R E L V R R K S A T D I G G L P G K L A D C R S T D P R K S E L Y V V E G D S A G G S A K S G R D S M F Q A I L P L R G K I I N V E K A R I D R V L K N T E V Q A I I T A L G T G I H D E F D I G K L R Y H K I V L M A D A D V D G Q H I S T L L L T L L F R F M R P L I E N G H V F L A Q P P L Y K L K W Q R S D P E F A Y S D R E R D G L L E A G L K A G K K I N K E D G I Q R Y K G L G E M D A K E L W E T T M D P S V R V L R Q V T L D D A A A A D E L F S I L M G E D V D A R R S F I T R N A K D V R F L D V
Cofactor	COFACTOR: Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000255|HAMAP-Rule:MF_01898, ECO:0000269|PubMed:16876125, ECO:0000269|PubMed:24015710}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000255|HAMAP-Rule:MF_01898}; Note=Mg(2+) required for DNA supercoiling, DNA relaxation, DNA cleavage and DNA decatenation, Mn(2+) substitutes for relaxation but not supercoiling or cleavage activity (PubMed:16876125). Ca(2+) does not substitute for supercoiling activity (PubMed:22844097). {ECO:0000269|PubMed:16876125, ECO:0000269|PubMed:22844097};
Active site	No current data
Pfam	PF00204 PF00986 PF02518 PF01751
InterPro	IPR002288 IPR011557 IPR003594 IPR036890 IPR020568 IPR014721 IPR001241 IPR013760 IPR013759 IPR013506 IPR018522 IPR006171 IPR034160