Uniprot ID	Q04119
Uniprot Name	PPN1_YEAST
Taxonomy ID	559292
Sequence	M V V V G K S E V R N V S M S R P K K K S L I A I L S T C V L F F L V F I I G A K F Q Y V S V F S K F L D D R G D N E S L Q L L N D I E F T R L G L T P R E P V I I K D V K T G K E R K L H G R F L H I T D I H P D P Y Y V E G S S I D A V C H T G K P S K K K D V A P K F G K A M S G C D S P V I L M E E T L R W I K E N L R D K I D F V I W T G D N I R H D N D R K H P R T E A Q I F D M N N I V A D K M T E L F S A G N E E D P R D F D V S V I P S L G N N D V F P H N M F A L G P T L Q T R E Y Y R I W K N F V P Q Q Q Q R T F D R S A S F L T E V I P G K L A V L S I N T L Y L F K A N P L V D N C N S K K E P G Y Q L L L W F G Y V L E E L R S R G M K V W L S G H V P P I A K N F D Q S C Y D K F T L W T H E Y R D I I I G G L Y G H M N I D H F I P T D G K K A R K S L L K A M E Q S T R V Q Q G E D S N E E D E E T E L N R I L D H A M A A K E V F L M G A K P S N K E A Y M N T V R D T Y Y R K V W N K L E R V D E K N V E N E K K K K E K K D K K K K K P I T R K E L I E R Y S I V N I G G S V I P T F N P S F R I W E Y N I T D I V N D S N F A V S E Y K P W D E F F E S L N K I M E D S L L E D E M D S S N I E V G I N R E K M G E K K N K K K K K N D K T M P I E M P D K Y E L G P A Y V P Q L F T P T R F V Q F Y A D L E K I N Q E L H N S F V E S K D I F R Y E I E Y T S D E K P Y S M D S L T V G S Y L D L A G R L Y E N K P A W E K Y V E W S F A S S G Y K D D
Cofactor	COFACTOR: Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000269|PubMed:8900207}; Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000269|PubMed:8900207}; Name=Co(2+); Xref=ChEBI:CHEBI:48828; Evidence={ECO:0000269|Ref.16}; Note=Divalent metal cations. Exopolyphosphatase activity is predominant in the presence of Co(2+), while endopolyphosphatase activity is predominant in the presence of Mg(2+) (PubMed:8900207, PubMed:25742176). Co(2+) is more effective than Mn(2+) for dATP phosphohydrolase activity (Ref.16). {ECO:0000269|PubMed:25742176, ECO:0000269|PubMed:8900207, ECO:0000269|Ref.16};
Active site	No current data
Pfam	PF00149
InterPro	IPR041805 IPR004843 IPR012358