Uniprot ID	Q04750
Uniprot Name	TOP1_MOUSE
Taxonomy ID	10090
Sequence	M S G D H L H N D S Q I E A D F R L N D S H K H K D K H K D R E H R H K E H K K D K D K D R E K S K H S N S E H K D S E K K H K E K E K T K H K D G S S E K H K D K H K D R D K E R R K E E K I R A A G D A K I K K E K E N G F S S P P R I K D E P E D D G Y F A P P K E D I K P L K R L R D E D D A D Y K P K K I K T E D I K K E K K R K S E E E E D G K L K K P K N K D K D K K V A E P D N K K K K P K K E E E Q K W K W W E E E R Y P E G I K W K F L E H K G P V F A P P Y E P L P E S V K F Y Y D G K V M K L S P K A E E V A T F F A K M L D H E Y T T K E I F R K N F F K D W R K E M T N D E K N T I T N L S K C D F T Q M S Q Y F K A Q S E A R K Q M S K E E K L K I K E E N E K L L K E Y G F C V M D N H R E R I A N F K I E P P G L F R G R G N H P K M G M L K R R I M P E D I I I N C S K D A K V P S P P P G H K W K E V R H D N K V T W L V S W T E N I Q G S I K Y I M L N P S S R I K G E K D W Q K Y E T A R R L K K C V D K I R N Q Y R E D W K S K E M K V R Q R A V A L Y F I D K L A L R A G N E K E E G E T A D T V G C C S L R V E H I N L H P E L D G Q E Y V V E F D F P G K D S I R Y Y N K V P V E K R V F K N L Q L F M E N K Q P E D D L F D R L N T G I L N K H L Q D L M E G L T A K V F R T Y N A S I T L Q Q Q L K E L T A P D E N V P A K I L S Y N R A N R A V A I L C N H Q R A P P K T F E K S M M N L Q S K I D A K K D Q L A D A R R D L K S A K A D A K V M K D A K T K K V V E S K K K A V Q R L E E Q L M K L E V Q A T D R E E N K Q I A L G T S K L N Y L D P R I T V A W C K K W G V P I E K I Y N K T Q R E K F A W A I D M T D E D Y E F
Cofactor	No current data
Active site	ACT_SITE 725 725 O-(3'-phospho-DNA)-tyrosine intermediate. {ECO:0000255|PROSITE-ProRule:PRU10130}.
Pfam	PF14370 PF01028 PF02919
InterPro	IPR011010 IPR013034 IPR013030 IPR001631 IPR018521 IPR025834 IPR014711 IPR014727 IPR013500 IPR008336 IPR036202 IPR013499