Uniprot ID	Q06AA3
Uniprot Name	RGN_PIG
Taxonomy ID	9823
Sequence	M S S I K I E C V L R E N C H C G E S P V W G E A S N S L L F V D I P A K K V C R W N A L S K Q V Q R V T L D A P V S S V A L R Q A G G Y V A T V G T K F C A L N W E D E S A V V L A A V D K D K K N N R F N D G K V D P A G R Y F A G T M A E E T A P A V L E R H Q G S L Y A L F A D H H V E K Y F D Q V D I S N G L D W S L D H K I F Y Y I D S L S Y S V D A F D Y D L Q T G K I S N R R S I Y K M E K E E H I P D G M C I D T E G K L W V A C Y N G G R V I R L D P E T G K R L Q T V K L P V D K T T S C C F G G K D Y S E M Y V T C A R D G L D P Q G L L Q Q P E A G G I F K I T G L G V K G L P P Y P Y A G
Cofactor	COFACTOR: Name=Zn(2+); Xref=ChEBI:CHEBI:29105; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250}; Name=Ca(2+); Xref=ChEBI:CHEBI:29108; Evidence={ECO:0000250}; Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Note=Binds 1 divalent metal cation per subunit. Most active with Zn(2+) and Mn(2+) ions. The physiological cofactor is most likely Ca(2+) or Mg(2+). {ECO:0000250};
Active site	ACT_SITE 204 204 Proton donor/acceptor. {ECO:0000250}.
Pfam	PF08450
InterPro	IPR011042 IPR008367 IPR013658 IPR005511 IPR039096