Uniprot ID	Q08493
Uniprot Name	PDE4C_HUMAN
Taxonomy ID	9606
Sequence	M E N L G V G E G A E A C S R L S R S R G R H S M T R A P K H L W R Q P R R P I R I Q Q R F Y S D P D K S A G C R E R D L S P R P E L R K S R L S W P V S S C R R F D L E N G L S C G R R A L D P Q S S P G L G R I M Q A P V P H S Q R R E S F L Y R S D S D Y E L S P K A M S R N S S V A S D L H G E D M I V T P F A Q V L A S L R T V R S N V A A L A R Q Q C L G A A K Q G P V G N P S S S N Q L P P A E D T G Q K L A L E T L D E L D W C L D Q L E T L Q T R H S V G E M A S N K F K R I L N R E L T H L S E T S R S G N Q V S E Y I S R T F L D Q Q T E V E L P K V T A E E A P Q P M S R I S G L H G L C H S A S L S S A T V P R F G V Q T D Q E E Q L A K E L E D T N K W G L D V F K V A E L S G N R P L T A I I F S I F Q E R D L L K T F Q I P A D T L A T Y L L M L E G H Y H A N V A Y H N S L H A A D V A Q S T H V L L A T P A L E A V F T D L E I L A A L F A S A I H D V D H P G V S N Q F L I N T N S E L A L M Y N D A S V L E N H H L A V G F K L L Q A E N C D I F Q N L S A K Q R L S L R R M V I D M V L A T D M S K H M N L L A D L K T M V E T K K V T S L G V L L L D N Y S D R I Q V L Q N L V H C A D L S N P T K P L P L Y R Q W T D R I M A E F F Q Q G D R E R E S G L D I S P M C D K H T A S V E K S Q V G F I D Y I A H P L W E T W A D L V H P D A Q D L L D T L E D N R E W Y Q S K I P R S P S D L T N P E R D G P D R F Q F E L T L E E A E E E D E E E E E E G E E T A L A K E A L E L P D T E L L S P E A G P D P G D L P L D N Q R T
Cofactor	COFACTOR: Name=a divalent metal cation; Xref=ChEBI:CHEBI:60240; Evidence={ECO:0000269|PubMed:17727341}; Note=Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions. {ECO:0000269|PubMed:17727341};
Active site	ACT_SITE 388 388 Proton donor. {ECO:0000250}.
Pfam	PF18100 PF00233
InterPro	IPR003607 IPR040844 IPR023088 IPR002073 IPR036971 IPR023174